标题:老年患者腹部手术后BNP的变化及其与心力衰竭的关系探讨
作者:李爱民 1,刘金洪 1,张 鹏 1,徐 心 2,李国威 2
(1.航天中心医院普通外科,北京 100049;
2.西安交通大学医学院附属西北医院普通外科,陕西 西安 710004)
卷次:
2013年24卷3期
【摘要】 目的 探讨B型钠尿肽(BNP)在老年患者腹部外科手术后的变化情况及其与术后心力衰竭的关
系。方法 采用化学发光免疫法动态监测64例老年患者腹部手术后BNP水平的变化,并按术后BNP水平分组,
观察各组患者心力衰竭发生的概率。结果 BNP水平≥400 pg/ml的患者心力衰竭的发生概率较BNP水平<
400 pg/ml的患者明显升高;经积极治疗后BNP水平显著下降。结论 老年患者腹部手术后BNP水平与心力衰
竭的发生密切相关,动态监测BNP水平能有效防治老年患者腹部手术后心力衰竭。
【关键词】 B型钠尿肽;老年外科;心力衰竭;腹部手术
【中图分类号】 R656 【文献标识码】 A 【文章编号】 1003—6350(2013)03—0345—02
Investigation of B-type natriuretic peptide changes in geriatric patients and its relationship with heart failure
after abdominal operation.
LI Ai-min 1, LIU Jin-hong 1, ZHANG Peng 1, XU Xin 2, LI Guo-wei 2. 1. Department of
General Surgery, Aerospace Center Hospital, Beijing 100049, CHINA; 2. Department of General Surgery, Xibei Hospital
Affiliated to Medical College of Xi'an Jiaotong University, Xi'an 710004, Shaanxi, CHINA
【Abstract】 Objective To investigate the changes of B-type natriuretic peptide in geriatric patients after ab-
dominal operation and its relationship with post-operational heart failure. Methods Using chemiluminescence
immunoassay to monitor the levels of B-type natriuretic peptide in geriatric patients after abdominal operation,
and to divide groups with its levels and observe the incidences of post-operational heart failure in different
groups. Results The incidence of heart failure in patients with BNP levels above 400 pg/ml increased signifi-
cantly than that in patients with BNP levels below 400 pg/ml. BNP level reduced significantly after effective treat-
ment of heart failure. Conclusion The changes of B-type natriuretic peptide in geriatric patients after abdominal op-
eration are closely related with post-operational heart failure. It is efficient to prevent heart failure in geriatric patients
post abdominal operation by means of dynamically monitoring the changes of B-type natriuretic peptide.
【Key words】 B-type natriuretic peptide; Geriatric surgery; Heart failure; Abdominal operation
·论 著·
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