标题：急性心肌梗死患者行PCI治疗后血浆NT-proBNP与Tei指数的变化及其与心功能分级的关系

      作者：曲 哲
    (武汉大学人民医院心内一科，湖北 武汉 430061)

      卷次： 2013年24卷3期

      【摘要】 目的 研究急性心肌梗死患者行PCI介入治疗后，不同心功能状态患者的NT-proBNP，Tei指数的
变化，及其与心功能分级的关系。方法 选取在我科治疗的70例急性心肌梗死患者作为研究对象，比较介入治
疗后不同心功能分级的患者Tei指数及血浆NT-proBNP的差异，并分析其相关性。结果 不同心功能分级患者
的Tei指数、NT-ProBNP以及LVEF差异均有统计学意义(P<0.05)，提示Tei指数与NT-ProBNP随心功能分级增加
而升高；LVEF则随心功能分级增加而降低。线性相关性分析发现，Tei指数与NT-proBNP呈正相关(P<0.05)；Tei
指数、NT-proBNP均与LVEF呈负相关(P<0.05)。结论 Tei指数与NT-proBNP可较为敏感的反映PCI治疗急性
心肌梗死后心功能的恢复情况，两者联合应用更为客观和准确。

      【关键词】 PCI；急性心肌梗死；NT-proBNP；Tei指数

      【中图分类号】 R542.2+2 【文献标识码】 A 【文章编号】 1003—6350（2013）03—0329—03


Correlation study of changes in Tei index, NT-pro brain natriuretic eptide and cardiac function classification
in patients with acute myocardial infarction after PCI.
QU Zhe. The First Department of Cardiology, Renmin
Hospital of Wuhan University, Wuhan 430061, Hubei, CHINA

【Abstract】 Objective To investigate the correlation between changes in Tei index, NT-pro brain natriuretic
eptide (NT-proBNP) and cardiac function classification in patients with acute myocardial infarction after percutaneous
coronary intervention (PCI). Methods Seventy patients with acute myocardial infarction were enrolled in this study.
The difference of NT-proBNP and Tei index were compared in patients of different cardiac function after PCI. The re-
lationship was analyzed. Results There was statistically significant difference in Tei index, NT-proBNP and LVEF
between the patients of different cardiac function after PCI (P<0.05). Tei index and NT-proBNP increased as the heart
dysfunction aggravated, while LVEF decreased as the heart dysfunction aggravated. Correlation analysis showed a sig-
nificant positive correlation between Tei index and NT-proBNP, but a significant negative correlation between Tei in-
dex, NT-proBNP and LVEF. Conclusion Tei index and NT-proBNP can sensitively reflect the cardiac function of pa-
tients with acute myocardial infarction after PCI. The combined application of Tei index and NT-proBNP would be
more objective and accurate.

      【Key words】 Percutaneous coronary intervention (PCI); Acute myocardial infarction; NT-pro brain natriuretic
eptide (NT-proBNP); Tei index