标题：加替沙星涂层导尿预防尿路感染效果观察

      作者：王春霞，李 萍，何春梅
    （德阳市第二人民医院神经科，四川 德阳 618000）

      卷次： 2013年24卷1期

      【摘要】 目的 探讨加替沙星涂层导尿对预防相关性尿路感染的作用。方法 将90例符合入选条件的患
者随机分为三组：A组（空白组）30例按常规方法留置尿管，B组（头孢哌酮钠组）30例导尿管外涂头孢哌酮钠注
射液，C组（加替沙星组）30例导尿管外涂加替沙星注射液。三组均在无菌操作下留置尿管，并按留置导尿专人
常规护理。结果 三组病例在留置导尿后不同时间段留取尿液及导尿管作细菌培养显示，C组的细菌培养阳性
率均低于其他两组。结论 加替沙星涂层导尿预防尿路感染是一种简便有效的方法。

      【关键词】 加替沙星；头孢哌酮；尿路感染；细菌培养

      【中图分类号】 R473.6 【文献标识码】 A 【文章编号】 1003—6350(2013)01—0151—03


Clinical effect of gatifloxacin coating in the prevention of catheter-associated urinary tract infection.
WANG
Chun-xia, LI Ping, HE Chun-mei. Department of Neurology, the Second People's Hospital of Deyang City, Deyang
618000, Sichuan, CHINA

【Abstract】 Objective To explore the role of gatifloxacin coating in the prevention of catheter-associated uri-
nary tract infections. Methods Ninety patients who met the inclusion criteria were randomly divided into three
groups. Patients in group A (the blank group, n=30) were treated by conventional methods of indwelling catheter. Pa-
tients in group B (the cefoperazone sodium group, n=30) were treated by catheter coated with cefoperazone sodium in-
jectPatients in Group C (gatifloxacin group, n=30) were treated by the catheter coated with gatifloxacin injection. The
patients all received aseptic indwelling catheter and routine medical care. Results The bacterial culture of urine spec-
imens in different time period showed that the positive rate of the bacteria in the gatifloxacin group was significnatly
lower than that in the other two groups. Conclusion Gatifloxacin coating is a simple and effective method for pre-
venting urinary tract infections in clinical practice.

      【Key words】 Gatifloxacin; Cefoperazone; Urinary tract infection; Bacterial culture