标题：89锶治疗恶性肿瘤骨转移性疼痛的效果和护理方法

      作者：冀小平 1，2，许新华 2，代文莉 2，覃斌芳 2，鲁明骞 2
    （1.三峡大学第一临床医学院肿瘤研究所，湖北 宜昌 443003；
2.宜昌市中心人民医院肿瘤科，湖北 宜昌 443003)

      卷次： 2013年24卷1期

      【摘要】 目的 探讨 89锶治疗骨转移癌患者疼痛的效果与护理方法。方法 42例均经病理学检查确诊的恶
性肿瘤患者，经ECT及X线平片、CT、MR证实骨转移，给予氯化锶注射治疗，观察疼痛缓解效果及不良反应，并
做好护理。结果 42例患者经评价疗效，患者疼痛缓解率为76.2%，其中乳腺癌效果最为明显，有效率为91.7%，
不良反应主要为骨髓抑制，33例患者出现白细胞、血小板及血色素下降，占78.6%，其中1例患者出现白细胞Ⅱ度
下降，其余患者均为Ⅰ度下降，无需特殊处理。结论 89锶可减轻恶性肿瘤骨转移，改善生活质量，方法简便、不
良反应较少，值得临床推广应用，要注意治疗前、治疗中及治疗后的护理。

      【关键词】 89锶；骨转移疼痛；疗效；护理

      【中图分类号】 R473.73 【文献标识码】 A 【文章编号】 1003—6350(2013)01—0147—03


Effect and nursing in the treatment of bone pain related to metastasis with Strontium-89.
JI Xiao-ping 1,2, XU
Xin-hua 2, DAI Wen-li 2, TAN Bin-fang 2, LU Ming-qian 2. 1. The Institute of Oncology, Three Gorges University, Yichang
443003, Hubei, CHINA; 2. Departmet of Oncology, Yichang Central People's Hospital, Yichang 443003, Hubei, CHINA

【Abstract】 Objective To explore the effect and nursing in treatment of bone pain related to metastasis with
Strontium-89. Methods The clinical data of 42 patients of malignant cancer with skeletal complications were retro-
spectively analyzed．Bone metastases were found by radionuclide bone imaging and proved by X-ray, CT or MRI.
Strontium (Sr-89)chloride was injected and the effect and adverse effect was observed. Nursing methods were con-
ducted by clinical nurse. Resluts The severity of bone pain before treatment and 12 weeks after treatment were com-
pared，76.2% of the 42 patients were observed pain parliament, especially those patients with mammary cancer with
efficient rate of 91.7%. The general adverse reactions and hematologic toxicity after treatment were observed. The
side effects were mild，33 cases occured 1 grade reversible myelosuppression with no treatment and 1 case got 2
grade myelosuppression who was cured by treatment. Several special nursing methods were conducted by clinical
nurses. Conclusion Strontium-89 are effective and safe for the management of malignant cancer related bone pain,
and special nursing should be paid great attention．

      【Key words】 Bone metastasis; Bone pain; Strontium-89( 89Sr); Effect; Nursing
·护 理·