标题：生物学指标与阿尔茨海默病的诊断

      作者：彭 誉，周 华，邱晨红，孙沁怡，王 锋，谢红娜，赵 中
    (南京医科大学附属苏州医院神经内科，江苏 苏州 215001)

      卷次： 2013年24卷1期

      【摘要】 阿尔茨海默病(Alzheimer's disease，AD)是痴呆中最常见的类型。到目前为止，临床诊断的AD患
者基本都已经处于中晚期，已没有可明显逆转已有损害或终止疾病进展的有效治疗措施。因此，治疗AD的希望
在于早期识别和早期干预。近年来，一系列新的生物学指标研究有助于阿尔茨海默病的早期识别。

      【关键词】 阿尔茨海默病；生物学指标；硝化应激；早期诊断

      【中图分类号】 R741 【文献标识码】 A 【文章编号】 1003—6350(2013)01—0117—04


Biological indicators and the diagnosis of Alzheimer's disease.
PENG Yu, ZHOU Hua, QIU Chen-hong, SUN
Qin-yi, WANG Feng, XIE Hong-na, ZHAO Zhong. Department of Neurology, Suzhou Hospital Affiliated to Nanjing
Medical University, Suzhou 215001, Jiangsu, CHINA
【Abstract】 Alzheimer's disease (AD) is the most common cause of dementia. But so far, most patients of clini-
cal identified Alzheimer's disease are mostly at the intermediate or advanced stage. No effective treatment is available
to reverse existing deficits or to arrest disease progression. The prospect of effective treatment for Alzheimer's disease
lies in early identification and early intervention. A series of recent studies has increased our opportunity to identify
early Alzheimer's disease in patients.

      【Key words】 Alzheimer's disease; Biological indicators; Nitrosative stress; Early diagnosis
·综 述·