标题：下咽癌病理分期与颈淋巴结转移的相关性研究

      作者：刘小云
    （宜春市人民医院耳鼻咽喉头颈外科，江西 宜春 336000）

      卷次： 2012年23卷24期

      【摘要】 目的 探讨下咽癌病理分期与颈淋巴结转移的相关性。方法 选取88例下咽癌患者，75例为梨状
窝癌，7例为环后癌，6例为下咽后壁癌，T2期15例、T3期32例、T4期41例，对患者淋巴结转移特点及其与病理分
期的关系进行统计分析。结果 88例下咽癌患者中有69例(78.41%)出现颈淋巴结转移，主要转移至颈部Ⅱ区、
Ⅲ区及Ⅳ区，三个部位转移率差异无统计学意义。T2期转移率为60.00%（9/15）、T3期转移率为90.63%（29/32）、T4
期转移率为100%（41/41），组间比较差异均有统计学意义（P<0.05）。随访患者1~3年，T2期患者1年生存率明显
高于T4期患者，T2期患者3年生存率明显高于T3期和T4期患者（P<0.05）。结论 下咽癌病理分期与颈淋巴结转
移明显相关，而颈淋巴结转移是影响下咽癌预后的重要因素，因此，可根据患者病理分期及颈淋巴结转移情况评
估患者预后及指导临床采取相应的治疗措施，以提高早期诊治效果。

      【关键词】 下咽癌；淋巴结转移；预后；病理分期

      【中图分类号】 R739.63 【文献标识码】 A 【文章编号】 1003—6350（2012）24—036—03<

br>Correlation between pathological stage of hypopharyngeal carcinoma and cervical lymph node metastasis.
LIU Xiao-yun.
Department of Otorhinolaryngology, Head and Neck Surgery, People's Hospital of Yichun City, Yichun 336000, Jiangxi, CHINA

【Abstract】 Objective To study the pathological stage of hypopharyngeal carcinoma and cervical lymph
node metastasis. Methods Eighty-eight patients of hypopharyngeal carcinoma were analyzed for the characters of
cervical lymph node metastasis, including 75 cases of pyriform sinus carcinoma, 7 cases of post-cricoid carcinoma, 6
cases of posterior hypopharyngeal wall, 15 cases in T2 stage, 32 cases in T3 stage, 41 cases in T4 stage. Results Of the
88 patients, 69 (78.41%) were found with cervical lymph node metastasis, mainly to the neckⅡ,Ⅲ,Ⅳarea, with no sta-
tistically significant differences in metastasis rate between the three locations. The metastasis rate of T2 stage, T3 stage,
T4 stage was 60.00% (9/15), 90.63% (29/32), 100% (41/41), respectively, with statistically significant difference (P<
0.05). The patients were followed up for 1~3 years. The one year survival rate in patients of T2 stage was significantly
higher than that in patients of T4 stage. The three years survival rate was significantly higher in patients of T2 stage than
patients of T3 and T4 stage (P<0.05). Conclusion The pathological stage of hypopharyngeal carcinoma is significantly
correlated with cervical lymph node metastasis, and cervical lymph node metastasis is an important factor affecting the
prognosis of hypopharyngeal carcinoma. Therefore, the pathological stage of hypopharyngeal carcinoma and cervical
lymph node metastasis can be used to evaluate the prognosis and guide clinical treatment to improve the clinical effect.

      【Key words】 Hypopharyngeal carcinoma; Lymph node metastasis; Prognosis; Pathological stage