标题：高脂血症性胰腺炎54例临床分析

      作者：郐大余 1，程 娟 2，高春霞 1，徐宝宏 1*
    (1.首都医科大学潞河教学医院消化内科，北京 101149；
2.中国人民解放军302医院门诊部皮肤科，北京 100039)

      卷次： 2012年23卷23期

      【摘要】 目的 探讨高脂血症性胰腺炎(Hyperlipidemic acute pancreatitis，HLAP)的临床特点及预后。
方法 回顾性分析我院2007年1月至2012年1月收治的54例HLAP的临床资料，并与同期入院的229例胆源性
胰腺炎(Acute biliary pancreatitis，ABP)进行比较。结果 HLAP患者以男性居多，男女比例为1.8:1，发病平均年
龄(38.0±7.8)岁，合并血糖升高者46例，占85.2%；脂肪肝者42例，占77.8%；血淀粉酶正常者9例，占16.7%；血淀
粉酶小于正常上限 3倍者 32例，占 59.3%。与ABP组比较，HLAP组男性比例高、发病年龄低；血糖水平及脂肪
肝发生率高；而血淀粉酶水平明显低于ABP组；重症胰腺炎的比例明显高于ABP组，平均住院日较ABP组长
(P<0.05)，胰腺炎复发次数多。结论 应重视对HLAP的早期诊断，尽早对高脂血症病因进行干预，积极进行饮
食习惯及生活方式的健康宣教，预防胰腺炎的复发。

      【关键词】 胰腺炎；高脂血症；临床特点；预后

      【中图分类号】 R657.5+1 【文献标识码】 A 【文章编号】 1003—6350（2012）23—028—03<

br>Clinical analysis of 54 patients with hyperlipidemic acute pancreatitis.
KUAI Da-yu 1, CHENG Juan 2, GAO
Chun-xia 1, XU Bao-hong 1*. 1. Department of Gastroenterology, the Luhe Hospital of the Capital Medical University,
Beijing 101149, CHINA; 2. Department of Dermatology, 302 Military Hospital of China, Beijing 100039, CHINA

【Abstract】 Objective To investigate the clinical characteristics and prognosis of hyperlipidemic acute pan-
creatitis (HLAP). Methods The clinical data of the patients with HLAP in our hospital from Jan. 2007 to Jan. 2012
was retrospectively analyzed (the HLAP group), and then compared with the clinical data of 229 patients with acute
biliary pancreatitis during the period (the ABP group). Results 65% of the patients were male, with male to female
ratio of 1.8:1 and the average onset age of 38 years old. Forty-six patients (85.2%) were complicated with blood glu-
cose elevation, and 42 patients (77.8%) were complicated with fatty liver. Nine patients (16.7%) were with normal he-
modiastase, and 32 were with hemodiastase three times lower than the upper normal limit. Compared with the ABP
group, the HLAP group had more male and younger patients, higher levels of blood glucose and higher incidence of
fatty liver, as well as lower levels of hemodiastase. The incidence of severe pancreatitis was significantly higher in the
HLAP group than the ABP group, with longer length of hospital stay and higher recurrence rate. Conclusion Early
diagnosis of HLAP is of great importance and treatment aiming at etiological factors should be carried out to allay the
symptoms and prevent relapse of the disease. So good eating habits and lifestyle is of great importance.

      【Key words】 Pancreatitis; Hyperlipidemia; Clinical characteristics; Prognosis
·临床研究·