标题：4164株病原菌的临床分布及药敏试验结果分析

      作者：董泽欣，夏永祥*
    （南京医科大学附属南京医院南京市第一医院检验科，江苏 南京 210006）

      卷次： 2012年23卷20期

      【摘要】 目的 分析4 164株病原菌的临床分布和药敏试验结果，为控制医院感染和抗菌药物的合理使用
提供依据。方法 回顾性分析 2010年南京市第一医院 4 164株病原菌的临床分布及对抗菌药物的药敏试验结
果。结果 4 164株病原菌中（真菌除外），革兰阳性球菌为855株（20.5%），以葡萄球菌属最多（552株），其次为肠
球菌属（303株）。葡萄球菌属对万古霉素和呋喃妥因高度敏感；屎肠球菌对多数药物的耐药率高于粪肠球菌，粪
肠球菌出现耐万古霉素菌株（1.7%）。结论 重视病原菌临床分布及耐药性监测，对控制院内感染和病原菌耐药
性的发展及临床抗菌素的合理使用有重要指导作用。

      【关键词】 病原菌；药敏试验；铜绿假单胞菌；金黄色葡萄球菌

      【中图分类号】 R446.5 【文献标识码】 A 【文章编号】 1003—6350（2012）20—109—03<

br>Clinical distribution and drug susceptibility testing of 4 164 pathogens.
DONG Ze-xin, XIA Yong-xiang. Nanjing
Hospital Affiliated to Nanjing Medical University, Nanjing 210006, Jiangsu, CHINA

【Abstract】 Objective To analyze the clinic distribution and drug susceptibility testing of 4 164 pathogenic
strains, and to provide guidance for the control of hospital infections and the rational use of antibiotics. Methods We
retrospectively analyzed the clinic distribution and drug susceptibility testing of 4 164 pathogenic strains in the Nan-
jing Hospital in 2010. Results A total of 4 164 pathogenic strains were isolated (except fungus), of which 929 strains
were gram positive coccus (22.3%), including 596 strains of staphylococcus and 333 strains of enterococcus. Staphylo-
coccus were found to be highly sensitive to nitrofurantoin and Vancomycin, and Enterococcus faecium were found to
have a higher sensitivity rate to most drugs than Enterococcus faecalis, which was resistant to vancomycin (1.7%).
Conclusion It is important to pay attention to the clinic distribution of pathogenic bacteria and detection of drug re-
sistance, which provides guidance for the control of hospital infections and the rational use of antibiotics.

      【Key words】 Pathogens; Drug susceptibility testing; Pseudomonas aeruginosa; Staphylococcus aureus
·检验与临床·