标题：亚甲蓝联合布比卡因在肛瘘术后镇痛中的应用效果观察

      作者：黄碧珊，梁振钊
    （海南医学院附属医院肛肠科，海南 海口 570102）

      卷次： 2012年23卷18期

      【摘要】 目的 观察肛瘘术后创面注射亚甲蓝的镇痛效果，探讨肛瘘术后创面镇痛的有效方法。方法 160
例肛瘘术后患者随机分为观察组和对照组各80例，观察组术后采用1%亚甲蓝2 ml与0.5%布比卡因2 ml混合创
面注射，对照组术后给予复方角菜酸脂栓一粒塞肛，观察两组的镇痛效果。结果 两组术后排便时、术后创面疼
痛程度以及创面愈合时间比较，观察组显著低于对照组（P<0.05）。结论 亚甲蓝联合布比卡因应用于肛瘘术后
镇痛效果好，可在临床上推广应用。

      【关键词】 肛瘘；镇痛；布比卡因；亚甲蓝

      【中图分类号】 R657.1+6 【文献标识码】 A 【文章编号】 1003—6350（2012）18—097—02<

br>Long-acting postoperative analgesic effect of methylene blue on anal fistula surgery.
HUANG Bi-shan LIANG
Zhen-zhao. Department of Anorectal Surgery, the Affiliated Hospital to Hainan Medical University, Haikou 570102,
Hainan Province, CHINA

【Abstract】 Objective To explore an effective analgesic method by studying the analgesic effect of methy-
lene blue injection into the operation wound after anal fistula surgery. Methods 160 cases of anal fistula patients
were randomly divided into observation group and control group. 1% methylene blue 2 ml mixed with 0.5% bupiva-
caine 2 ml was injected into the operation wounds in the observation group,, and one compound carraghenates acid
grease suppository was given rectally in control group. The analgesic effects in two groups were compared and statisti-
cally analyzed. Results Compared with those in the control group, the time of resumption of the defecation after op-
eration and wound healing time were significantly shorter and postoperative wound pain score was significantly lower
in the observation group (P< 0.05). Conclusion Injection of methylene blue mixed with bupivacaine into surgical
wound is effective in postoperative analgesia in anal fistula surgery and can be widely applied in clinical practice.

      【Key words】 Anal fistula; Analgesia; Methylene blue; Bupivacaine
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