标题：脑出血微创穿刺治疗术后抑郁状况的研究

      作者：卢少泉 1，黄良珍 2
    （海南省人民医院保健中心一区 1、神经外科 2，海南 海口 570311）

      卷次： 2012年23卷18期

      【摘要】 目的 探讨微创穿刺治疗术对脑出血患者神经功能恢复和卒中后抑郁（PSD）发生率的影响。
方法 以107例分别接受微创血肿穿刺术治疗(n=65)和传统开颅血肿清除术治疗(n=42)的脑出血患者为研究对
象。在入院、病程30 d和90 d时应用美国国立卫生研究院卒中量表(NIHSS)评定患者神经功能缺损情况，在病程
30 d和90 d时应用Zung抑郁自评量表(SDS)评定抑郁状态，比较两种治疗方法术后对PSD发生率的影响，并分析
PSD与患者神经功能缺损程度的关系。结果 在病程30 d和90 d，微创治疗组NIHSS评分、PSD发生率均低于
开颅治疗组(P<0.05)。SDS评分与NIHSS评分之间均存在正相关关系。结论 微创穿刺颅内血肿清除术是治疗
脑出血的一种有效方法，不仅患者神经功能恢复良好，而且术后PSD发生率较传统开颅组低。脑出血术后SDS
评分与术后神经功能缺损程度呈正相关。

      【关键词】 脑出血；抑郁；微创血肿穿刺术；开颅血肿清除术

      【中图分类号】 R743.34 【文献标识码】 A 【文章编号】 1003—6350（2012）18—004—03<

br>Treatment of depression in patients with cerebral hemorrhage by minimally invasive puncture.
LU Shao-quan 1,
HUANG Liang-zhen 2. The First Health Care Center 1, Department of Neurosurgery 2, People's Hospital of Hainan
Province, Haikou 570311, Hainan, CHINA

【Abstract】 Objective To discuss the effect of minimally invasive puncture on cerebral hemorrhage neurolog-
ical recovery and the incidence of post-stroke depression (PSD). Methods One hundred and seven patients with cere-
bral hemorrhage were treated by minimally invasive puncture (the study group, n=65) and traditional hematoma cra-
niotomy remove (the control group, n=42). The patients’neural function defects were assessed by the National Insti-
tutes of Health Stroke scale (NIHSS) at admission, 30 d and 90 d after treatment. Patients’depression was assessed
by the Zung self-rating depression scale (SDS) 30 d and 90 d after treatment. The incidence of PSD were compared
between the two groups, and the relationship between PSD and patients neural function defect degree were analyzed.
Results 30 d and 90 d after treatment, NIHSS scores and the incidence of PSD in the study group were significant-
ly lower than those in the control group (P<0.05). NIHSS scores were positively correlated to SDS score. Conclu-
sion Minimally invasive puncture removal of intracranial hematomas is a kind of effective method for treating cere-
bral hemorrhage, with good recovery of neurological function and low incidence of PSD. There is a positive correla-
tion between SDS score and disorders of nervous functions degree.

      【Key words】 Cerebral hemorrhage; Depression; Minimally invasive puncture hematoma; Hematoma cranioto-
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