标题：星状神经节阻滞治疗围绝经期失眠症26例疗效分析

      作者：刘群会，朱祖欣
    (恩施州中心医院神经内科，湖北 恩施 445000)

      卷次： 2012年23卷12期

      【摘要】 目的 观察星状神经节阻滞治疗围绝经期失眠症患者的临床疗效。方法 选择我院门诊及住院
确诊为围绝经期失眠症的患者26例，采用前入路径行星状神经节阻滞(SGB)治疗20次，观察睡眠改善情况，检测
治疗前后血雌二醇(E2)，促卵泡生成素(FSH)、黄体生成素(LH)的变化，用汉密尔顿焦虑量表(Hamilton anxiety
scale HAMA)评定患者焦虑症状的严重程度。结果 血中 E2由治疗前的(33.13±18.26) pmol/L升至(153.64±
86.57) pmol/L (t=-8.00，P<0.01)，FSH由治疗前的(52.74±20.16) U/L降至(37.96±12.48) U/L (t=2.08，P<0.05)，LH由
治疗前的(36.09±13.34) U/L降至(25.35±7.51) U/L(t=2.21，P<0.05)。睡眠改善的总有效率为84.6%。HAMA评分
由治疗前的(19.9±6.87)分降至(11.4±4.1)分(t=3.35，P<0.01)。结论 SGB治疗能有效改善患者失眠和焦虑症状，
能调节围绝经期失眠症患者的神经平衡失调。

      【关键词】 星状神经节；阻滞；围绝经期；失眠症

      【中图分类号】 R711 【文献标识码】 A 【文章编号】 1003—6350(2012)12—007—03<

br>Effect of stellate ganglion block in the treatment of 26 perimenopausal patients with insomnia.
LIU Qun-hui,
ZHU Zu-xin. Department of Neurology, the Central Hospital of Enshi, Enshi 445000, Hubei, CHINA

【Abstract】 Objective To explore the clinical effect of stellate ganglion block (SGB) in the treatment of peri-
menopausal patients with insomnia. Methods Twenty-six perimenopausal patients diagnosed as insomnia in the Cen-
tral Hospital of Enshi were treated by SGB for 20 times via the anterior approach. The improvements of sleep was ob-
served, the severity of anxiety symptoms was evaluated by Hamilton Anxiety Scale (HAMA), and the changes of blood
estradiol (E2), Follicle-Stimulating Hormone (FSH) and luteinizing hormone (LH) were detected. Results The serum
level of E2 increased from (33.13±18.26) pmol/L to (153.64±86.57) pmol/L (t=-8.00, P<0.01), FSH decreased from
(52.74±20.16) U/L to (37.96±12.48) U/L (t=2.08, P<0.05), and LH reduced from (36.09±13.34) U/L to (25.35±7.51) U/L
(t=2.21, P<0.05). The total efficient rate of improvement of sleep was 84.6%, and the HAMA score decreased from
(19.9±6.87) to (11.4±4.1) (t=3.35, P<0.01). Conclusion SGB can regulate perimenopausal patients with insomnia in
nervous imbalance, and it may be effective in improving insomnia.

      【Key words】 Stellate ganglion; Block; Perimenopausal; Insomnia
·论 著·