标题：144例甲状腺结节患者临床诊断分析

      作者：李 俊
    (柳州市柳铁中心医院普外一科，广西 柳州 545007)

      卷次： 2012年23卷9期

      【摘要】 目的 探讨临床特征、实验室检查(TSH等)和B超在甲状腺结节诊断中的价值。方法 对我院144
例甲状腺结节患者进行分析，其中良性结节93例，恶性结节51例。对两组在临床特征，实验室检查和B超结果
方面进行比较分析。结果 在良性组和恶性组比较中，年龄、性别、血清TSH和FT4水平、甲状腺自身免疫性疾
病、甲状腺功能异常、单一结节差异无统计学意义(P>0.05)。超声显示结节出现可疑征象：微小钙化、边界不规则
和低回声结节直径≥2 cm是恶性结节的独立危险因素，差异有统计学意义(P<0.05)。结论 微小钙化、边界不规
则和低回声结节直径≥2 cm是恶性甲状腺结节的独立危险因素，需进一步检查。

      【关键词】 临床特征；实验室检查；B超；甲状腺结节；诊断

      【中图分类号】 R581 【文献标识码】 A 【文章编号】 1003—6350(2012)09—080—03<

br>Analysis on the clinical diagnosis of 144 cases of thyroid nodule.
LI Jun. The First Department of General Surgery,
Liutie Central Hospital of Liuzhou City, Liuzhou, 545007, Guangxi, CHINA

【Abstract】 Objective To study the value of clinical features, laboratory examination and ultrasound in the
diagnosis of thyroid nodule. Methods 144 patients with thyroid nodule were studied, including 93 benign nodules
(the benign group) and 51 malignant nodules (the malignant group). The clinical features, laboratory examination and
ultrasound features were compared between the two groups. Results There were no statistically significant differenc-
es in age, gender, serum TSH and FT4 levels, thyroid dysfunction and autoimmune disease between the two groups
(P>0.05). Ultrasound showed differences when suspected characteristics were found in the nodules of the malignant
group, such as microcalcifications, central flow, border irregularity and hypoechogenicity. After the multivariate analy-
sis, the model obtained showed border irregularity, microcalcifications and nodule size over 2 cm as predictive factors
of malignancy (P<0.05). Conclusion Border irregularity, microcalcifications and nodule size over 2 cm are the inde-
pendent risk factors for malignant thyroid nodule.

      【Key words】 Clinical features; Laboratory examination; Ultrasound; Thyroid nodule; Diagnosis