标题：冠心病患者心率变异性与踝臂指数的相关性研究

      作者：刘向阳，范文茂，李爱华，万槐斌
    (韶关市粤北人民医院心内科，广东 韶关 512026)

      卷次： 2012年23卷9期

      【摘要】 目的 探讨冠心病患者心率变异(HRV)与踝臂指数(ABI)的关系。方法 选择80例冠心病患者(A
组)及76例非冠心病患者(B组)，行动态心电图检查，取时域指标SDNN代表HRV，同时测量ABI，分析冠心病患
者HRV与ABI的相关性。结果 冠心病组(A组)与非冠心病组(B组)相比，其HRV明显降低，同时ABI也明显降
低，其差异有显著统计学意义(P<0.01)；并且HRV与ABI呈正相关(r=0.358，t=2.338，P<0.01)。结论 冠心病患者
HRV及ABI降低，并且HRV是ABI的独立影响因素。

      【关键词】 冠心病；心率变异；踝臂指数

      【中图分类号】 R541.4 【文献标识码】 A 【文章编号】 1003—6350(2012)09—013—02<

br>Correlation between heart rate variability and ankle-brachial index in coronary heart disease.
LIU Xiang-yang,
FAN Wen-mao. LI Ai-hua, WAXI Kuai-bin. Department of Cardiology, Yuebei Hospital, Shaoguan 512026, Guangdong,
CHINA

【Abstract】 Objective To study the changes of heart rate variability(HRV) and ankle-brachial Index (ABI) and il-
lustrate the correlation between heart rate variability(HRV) and ABI in coronary heart disease (CHD). Methods 80 CHD
patients in group A and 76 patients without CHD in group B were studied. The time domain parameters of 24 hours
HRV were detected by 24 hour electrocardiographic monitoring; ABI was measured by VP- 1000 Automatic Arterio-
sclerosis Measurement System after hospitalization. Results The HRV value[(108.85±28.24 ms VS 121.76±28.00
ms)] and the ABI value [(1.09±0.12 VS 1.13±0.07)] was lower in Group A than those in Group B (P<0.01), and HRV
value was positively correlation with NT-proBNP(r=0.358，t=2.338，P<0.01). Conclusion The HRV value and the
ABI value in CHD patients are low, which suggests that lower HRV is a potential risky factor that may affect the ABI
value in patients with CHD.

      【Key words】 Coronary heart disease; Heart rate variability; Ankle-brachial index