标题：全麻下鼻窦开放术后拔管期间防止呛咳的研究

      作者：甘 敏，钟伟州，邹小梅，龚建华，周克城
    (深圳市龙岗区横岗人民医院麻醉科，广东 深圳 518115)

      卷次： 2012年23卷8期

      【摘要】 目的 探讨预防全麻下鼻窦开放术后拔管期间呛咳的方法。方法 选取2011年1月~2月于本院
进行全麻下鼻窦开放术治疗的 140例患者为研究对象，随机分为A组和B组各 70例，A组术毕前导管内注入利
多卡因，B组术毕前导管内注入丁卡因，后将两组患者呛咳发生率及拔管前5 min、拔管后即刻、拔管后5 min的
HR、MAP、SBP、DBP、BIS及血糖、皮质醇、β内啡肽水平进行统计及比较。结果 B组呛咳发生率低于A组，B
组HR、MAP、SBP、DBP、BIS及血糖、皮质醇、β内啡肽水平波动幅度均小于A组，P均＜0.05，差异均有统计学意
义。结论 丁卡因在预防全麻下鼻窦开放术后拔管期间呛咳中的效果更好，患者的应激反应更轻。

      【关键词】 丁卡因；利多卡因；全麻下鼻窦开放术；预防；拔管；呛咳

      【中图分类号】 R765.9 【文献标识码】 A 【文章编号】 1003—6350(2012)08—013—03<

br>Study on the prevention of irritating cough during extubation after sinus surgery under general anesthesia.
GAN Min, ZHONG Wei-zhou, ZOU Xiao-mei, GONG Jian-hua, ZHOU Ke-cheng.
Anesthetic Department, Henggang
People's Hospital of Longgang District of Shenzhen City, Shenzhen 518115 Guangdong, CHINA

【Abstract】 Objective To study the method of preventing irritating cough during extubation after sinus sur-
gery under general anesthesia. Methods 140 patients treated with sinus surgery under general anesthesia in our hos-
pital from January 2009 to July 2011 were selected. The patients were randomly divided into group A and group B,
with 70 cases in each group. Patients in group A were treated with lidocaine intraductal injection, while those in group