标题：两种中心静脉导管相关性感染的临床观察

      作者：高立平
    (中国人民解放军第187中心医院感染控制科，海南 海口 571159)

      卷次： 2012年23卷7期

      【摘要】 目的 评价抗感染中心静脉导管在减少重症监护病房(ICU)患者导管相关性感染(CRI)中的作
用。方法 将 248例在 ICU留置中心静脉导管的患者随机分成普通中心静脉导管组(对照组 120例)和抗感染
中心静脉导管组(抗感染组 128例)，观察两组CRI的发生率和病原菌分布情况。结果 抗感染组的CRI发生
率明显低于对照组(6.3%vs14.2%)，差异有统计学意义(P＜0.05)。CRI的病原菌为金黄色葡萄球菌、鲍曼不动
杆菌、阴沟肠杆菌、肠球菌、肺炎克雷伯菌和白色念珠菌，但两组患者CRI病原菌分布比较，差异无统计学意
义(P＞0.05)。结论 抗感染中心静脉导管可明显降低 ICU患者CRI的发生率。

      【关键词】 抗感染中心静脉导管；普通中心静脉导管；导管相关性感染

      【中图分类号】 R473.6 【文献标识码】 B 【文章编号】 1003—6350（2012）07—146—02<

br>Clinical investigation of catheter-related infections in two central venous catheters.
GAO Li-ping. Department of
Infection-control, the 187th Central Hospital of PLA, Haikou 571159, Hainan, CHINA

【Abstract】 Objective To evaluate the effect of reducing intravenous catheter-ralated infection (CRI) using anti-
septic impregnated central venous catheter in patients in intensive care unit (ICU). Methods 248 patients treated in ICU
who needed intravascular catheterization were randomly divided into the control group (120 cases, treated with ordinary
central venous catheter) and the antiseptic group (128 cases, treated with antiseptic impregnated central venous catheter).
The incidence of CRI and pathogenic distribution were observed. Results The incidence of CRI in the antiseptic group
was significantly lower than that of the control group (6.3% vs 14.2%, P<0.05). The pathogens of CRI were Staphylococcus
aureus, Acinetobactor baumannii, E. cloacae, enterococcus, Klebsiella pneumoniae and Candida albicans. Pathogenic distribu-
tion between the two groups showed no statistically significant difference (P>0.05). Conclusion Antiseptic impregnated
central venous catheter can obviously reduce the incidence of CRI in patients in ICU.

      【Key words】 Antiseptic impregnated central venous catheter; Ordinary central venous catheter; Catheter-relat-
ed infection