标题：糖尿病合并脂肪肝的临床特征分析

      作者：马松炎，简希尧，徐永辉，文毅，张弟
    （惠州市第三人民医院消化内科，广东惠州516002）

      卷次： 2012年23卷6期

      【摘要】目的探讨糖尿病合并脂肪肝临床特征，寻找相关危险因素。方法2006 年11 月至2011 年2 月在
我院门诊及住院治疗的108 例2 型糖尿病患者分为两组，其中合并非酒精性脂肪肝组（NAFL 组）52 例，不合并
非酒精性脂肪肝组（非NAFL组）56 例，检测体重指数、腰围、收缩压、舒张压、空腹血糖、空腹胰岛素、血胰岛素
抵抗指数、糖化血红蛋白、谷丙转氨酶酶、谷草转氨酶、C 反应蛋白、尿酸、总胆固醇、甘油三酯、低密度脂蛋白
和高密度脂蛋白等相关因素并组间比较，NAFL 与各种影响因素间相关性检验用Logistic 多因素逐步回归分
析。结果NAFL组BMI、腰围、FBG、FINS、GHbA1c、UA、TC、TG、HDL及LDL水平与非NAFL组比较，差异有
统计学意义（P<0.05 或P<0.01）；BMI、腰围、TG及LDL与NAFL发生密切相关。结论BMI、腰围、TG及LDL是
发生2型糖尿病合并NAFL的高危因素。

      【关键词】糖尿病；脂肪肝；临床特征

      【中图分类号】R587.1 【文献标识码】A 【文章编号】1003—6350（2012）06—028—03
r>Clinical feather of diabetes combined with fatty liver.
MA Song-yan，JIAN Xi-yao, XU Yong-hui, WEN Yi, ZHANG
Di. The Third People's Hospital of Huizhou City, Huizhou 516002, Guangdong, CHINA
【Abstract】Objective To investigate the clinical features of diabetes combined with fatty liver (NAFL) and
its risk factors. Methods 108 cases with type 2 diabetes patients from November 2006 to February 2011 were divided
into two groups, there were 52 cases in NAFL group and 56 cases in the non-NAFL group, the body mass index
(BMI), waist circumference, systolic blood pressure, diastolic blood pressure, fasting glucose (FBG), fasting insulin
(FINS), insulin resistance index, glycosylated hemoglobin (GHBA1c), enzymes alanine aminotransferase, aspartate
aminotransferase, C-reactive protein, uric acid (UA), total cholesterol (TC), triglycerides, low density lipoprotein
(LDL) and high density lipoprotein (HDL) and other related factors were detected and compared. Logistic multivariate
regression analysis were used to process the correlation between NAFL and the various factors. Results Compared
with the non-NAFL group, there were significant difference between BMI, waist circumference, FBG, FINS, GHbA1c,
UA, TC, TG, HDL and LDL levels (P<0.05 or P<0.01), there were closely correlation between the occurrence
of NAFL and BMI, waist circumference, TG and LDL. Conclusion BMI, waist circumference, TG and LDL are risk
factors of type 2 diabetes combined with NAFL.
【Key words】Diabetes; Fatty liver; Clinical features