标题：左旋炔诺酮宫内缓释系统治疗围绝经期功血的90 例疗效观察

      作者：李红
    （兴宁市人民医院妇产科，广东兴宁514500）

      卷次： 2012年23卷5期

      【摘要】目的观察左炔诺孕酮宫内缓释系统治疗围绝经期功血的临床疗效。方法对90 例围绝经期
功血患者采用左炔诺孕酮宫内缓释系统治疗，全部病例均于每次月经后3～7 d 内随访，共随访6 个月。记录
服药前后月经出血情况、子宫内膜厚度、子宫大小、双侧卵巢大小、血红蛋白含量的变化。结果患者用药前
后的子宫大小、卵巢体积比较差异无统计学意义（P＞0.05）；患者在用药前的子宫内膜厚度为(13.69±0.35)mm，
用药后为(7.36±1.29) mm，治疗前后的子宫内膜厚度改变比较差异有统计学意义(P＜0.05)；患者用药前的血
红蛋白含量为(53.66±3.22) g/L，治疗后为(102.96±4.62) g/L，治疗前后的血红蛋白含量改变比较差异有统计学
意义(P＜0.05)。结论左旋炔诺酮宫内缓释系统治疗围绝经期功血，能有效减少月经量，控制子宫内膜增生，增
加血红蛋白含量，临床疗效满意，值得临床推广。

      【关键词】左旋炔诺酮宫内缓释系统；围绝经期功血；月经量；子宫内膜厚度；血红蛋白量

      【中图分类号】R711.52 【文献标识码】A 【文章编号】1003—6350（2012）05—069—02
r>Clinical study of levonorgestrel-releasing intrauterine system in the treatment of perimenopausal uterine
bleeding.
LI Hong. The People's Hospital of Xingning City, Xingning 514500, Guangdong, CHINA
【Abstract】Objective To observe the clinical efficacy of levonorgestrel-releasing intrauterine system in the treatment
of perimenopausal uterine bleeding. Methods 90 patients with perimenopausal uterine bleeding were treated with
levonorgestrel-releasing intrauterine system, and all the patients were followed up 3~7 days after menstrual for 6 months.
The menstrual flow, endometrial thickness, uterine size, ovaries size, and hemoglobin changes before and after treatment
were recorded. Results There were no statistically significant differences in the uterine size, ovarian volume before and
after treatment (P>0.05). The endometrial thickness was (13.69±0.35) mm before treatment and (7.36±1.29) mm after
treatment (P<0.05), showing statistically significant difference. The hemoglobin content was (53.66±3.22) g/L before
the treatment, significantly lower than (102.96±4.62) g/L after treatment (P<0.05). Conclusion Levonorgestrel-releasing
intrauterine system for treatment of perimenopausal uterine bleeding can effectively reduce the menstrual flow,
control the endometrial hyperplasia, and increase hemoglobin levels, with satisfactory clinical result, which is worthy
to be promoted in clinical practice.
【Key words】Levonorgestrel-releasing intrauterine system; Perimenopausal uterine bleeding; Menstrual flow;
Endometrial thickness; Hemoglobin