标题：2014—2020年重庆市九龙坡区恶性肿瘤疾病负担分析

      作者：贺明 1，陶然 1，汤成 1，梁艳 1，马周俊 1，骆致 1，李小清 2    1.重庆市九龙坡区疾病预防控制中心慢性非传染性疾病和地方病预防控制科，重庆 400039；2.重庆市中医院肝病科，重庆 400021

      卷次： 2024年35卷3期

      【摘要】 目的 分析重庆市九龙坡区恶性肿瘤疾病负担特征，为开展恶性肿瘤防治提供建议。方法 收集2014—2020年重庆市九龙坡区恶性肿瘤发病死亡资料，采用 SPSS19.0软件分析恶性肿瘤发病率、标化发病率(ASRIC)、死亡率、标化死亡率(ASRMC)、伤残调整寿命年(DALY)、早死所致的寿命损失年(YLL)、伤残所致寿命损失年(YLD)等指标。利用χ2检验比较不同性别间发病率和死亡率。结果 2014—2020年重庆市九龙坡区恶性肿瘤年均粗发病率、ASRIC分别为287.25/10万、206.24/10万，其中男性恶性肿瘤年均粗发病率、ASRIC分别为337.34/10万、228.71/10万，女性分别为238.41/10万、182.66/10万，历年恶性肿瘤年均粗发病率不同性别间比较差异均有统计学意义(P<0.05)；2014—2020年重庆市九龙坡区恶性肿瘤年均粗死亡率、ASRMC分别为180.41/10万、118.72/10万，其中男性恶性肿瘤年均粗死亡率、ASRMC分别为247.70/10万、158.86/10万，女性分别为114.81/10万、78.68/10万，历年恶性肿瘤粗死亡率不同性别间比较差异均有统计学意义(P<0.05)；2014—2020年重庆市九龙坡区恶性肿瘤年均YLL率、YLD率、DALY率分别为 47.02‰、1.78‰、48.79‰；DALY率构成中，YLL率构成占比(96.37%)明显大于YLD率占比(3.63%)。结论 2014—2020年重庆市九龙坡区恶性肿瘤的疾病负担仍较重，尤其是男性人群，YLL率是疾病负担过重的主要原因，应采取针对性措施进行管理和预防。
      【关键词】 重庆；九龙坡区；恶性肿瘤；疾病负担；发病率；死亡率
      【中图分类号】 R730 【文献标识码】 A 【文章编号】 1003—6350（2024）03—0345—04

Analysis on disease burden of malignant tumor in Jiulongpo District of Chongqing from 2014 to 2020.
HE Ming 1,TAO Ran 1, TANG Cheng 1, LIANG Yan 1, MA Zhou-jun 1, LUO Zhi 1, LI Xiao-qing 2. 1. Department of ChronicNon-communicable Diseases and Endemic Disease Prevention and Control, Chongqing Jiulongpo District for Disease Controland Prevention Center, Chongqing 400039, CHINA; 2. Department of Hepatology, Chongqing Hospital of TraditionalChinese Medicine, Chongqing 400021, CHINA
【Abstract】 Objective To analyze the characteristics of disease burden of malignant tumor in Jiulongpo Districtof Chongqing, so as to provide suggestions for prevention and treatment of malignant tumor. Methods The clinical da-ta of patients with malignant tumor who died in Jiulongpo District of Chongqing from 2014 to 2020 were collected. Theincidence, age standardized rates of incidence by Chinese standard population (ASRIC), mortality, age standardized ratesof mortal by Chinese standard population (ASRMC), disability adjusted life years (DALY), years of life lost with prema-ture death (YLL), years lived with disability (YLD) were analyzed by SPSS19.0. The incidence and mortality were com-pared by χ2 test. Results The annual average crude incidence and ASRIC of malignant tumor were 287.25 per 100 000people and 206.24 per 100 000 people in Jiulongpo District of Chongqing from 2014 to 2020, with 337.34 per 100 000people and 228.71 per 100 000 people in male patients and 238.41 per 100 000 people and 182.66 per 100 000 people infemale patients. There was a significant difference in the crude incidence rate of malignant tumor between males and fe-males (P<0.05). The annual average crude mortality and ASRMC of malignant tumor were 180.41 per 100 000 peopleand 118.721 per 100 000 people in Jiulongpo District of Chongqing from 2014 to 2020, with 247.70 per 100 000 peopleand 158.86 per 100 000 people in male patients and 114.81 per 100 000 people and 78.68 per 100 000 people in femalepatients. There was a significant difference in the crude mortality of malignant tumor between males and females (P<0.05). The annual average YLL rate, YLD rate, and DALY rate were 47.02‰ , 1.78‰ , 48.79‰, respectively. In DALYrate composition, the proportion of YLL (96.37%) was significantly higher than that of YLD (3.63%). Conclusion Thedisease burden of malignant tumors was still heavy, especially for males. YLL rate was the leading cause of overburdenin Jiulongpo District of Chongqing from 2014 to 2020. Therefore, effective measures should be taken for managementand prevention to reduce the occurrence of disease burden.
      【Key words】 Chongqing; Jiulongpo District; Malignant tumor; Disease burden; Incidence; Mortality