标题:高脂血症性急性胰腺炎病因、发病机制及严重程度评估研究新进展
作者:陆秀仙,覃玉桃 综述 吴英宁 审校 右江民族医学院附属医院放射科,广西 百色 533000
卷次:
2023年34卷13期
【摘要】 近年来,高脂血症引发的急性胰腺炎日益流行,其发病年轻化,病情重且反复,预后差,引起了临床医生的普遍关注和重视。急性胰腺炎主要是由高甘油三酯所致,发病机制可能主要与游离脂肪酸损害腺泡细胞、胰腺微循环障碍、胰腺炎性介质加速激活等有关,在严重程度上目前有几种比较常用的评分系统。本文就高脂血症性急性胰腺炎的发病原因、发病机制及严重程度评估进行综述,重点阐述其严重程度评估。
【关键词】 高脂血症性;急性胰腺炎;病因;发病机制;严重程度
【中图分类号】 R589.2 【文献标识码】 A 【文章编号】 1003—6350(2023)13—1959—04
Recent progress in etiology, pathogenesis, and severity evaluation of hyperlipidemic acute pancreatitis.
LUXiu-xian, QIN Yu-tao, WU Ying-ning. Department of Radiology, Affiliated Hospital of Youjiang Medical College forNationalities, Baise 533000, Guangxi, CHINA【Abstract】 In recent years, acute pancreatitis caused by hyperlipidemia has become increasingly popular. It ischaracterized with young onset age, severe disease condition, and recurrence, and poor prognosis, which has attractedwidespread attention from clinicians. It is mainly caused by hypertriglyceride, and its pathogenesis may be mainly relat-ed to free fatty acids' damage to acinus cells, pancreatic microcirculation disorder, the accelerated activation of pancreat-ic inflammatory mediators, etc. In terms of severity, there are several commonly used scoring systems. This paper re-views the pathogenesis, pathogenesis, and severity evaluation of hyperlipidemic acute pancreatitis, focusing on the sever-ity assessment.
【Key words】 Hyperlipemia; Acute pancreatitis; Etiology; Pathogenesis; Degree of severity
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