标题：CK-MB在儿童支气管肺炎辅助检查中的临床意义

      作者：朱家良，李善文，施会敏，张爱青，甘卫华
    (南京医科大学第二附属医院儿科，江苏 南京 210003)

      卷次： 2016年27卷4期

      【摘要】 目的 探讨血清磷酸肌酸同工酶(CK-MB)检测在儿童轻症支气管肺炎辅助检查中的临床意义，以期
指导临床诊治。方法 收集2015年1~8月85例本院收治的轻症支气管肺炎患儿，分为学龄期组(7~14岁) 6例、学
龄前期组(4~6岁) 22例和婴幼儿期组(0~3岁) 57例，入院时常规检测患儿CK-MB的数值，分析其在不同年龄组中
的变化情况。结果 85例住院患儿中男性 49例，女性 36例，婴幼儿组 11例患儿CK-MB升高(19%)，学龄前期患
儿组 1例升高(5%)，学龄期组患儿无一例CK-MB升高。男性患儿CK-MB数值为(2.40±1.76) ng/ml，女性患儿为
(2.93±1.96) ng/ml，两者比较差异无统计学意义(P>0.05)。婴幼儿组患儿CK-MB为(3.23±1.84) ng/ml，学龄前期组为
(1.58±1.27) ng/ml，学龄期组为(0.75±0.57) ng/ml，婴幼儿组支气管肺炎患儿血液CK-MB数值较学龄前期和学龄期
患儿显著升高，差异均有统计学意义(P<0.05)。结论 CK-MB是目前临床判断患儿心肌受损的经典检测指标，婴
幼儿支气管肺炎轻症合并心肌受损的发生概率相对较高，血清CK-MB的检测应作为婴幼儿支气管肺炎的常规检
查，可以使患儿得到更好的诊治。对于学龄前期和学龄期轻症支气管肺炎患儿，血清CK-MB可不作为临床常规的
辅助检查。

      【关键词】 磷酸肌酸同工酶；支气管肺炎；儿童；辅助检查；临床意义

      【中图分类号】 R725.6 【文献标识码】 A 【文章编号】 1003—6350（2016）04—0556—02


Clinical value of serum CK-MB in the auxiliary examination of children with bronchial pneumonia.
ZHU
Jia-liang, LI Shan-wen, SHI Hui-min, ZHANG Ai-qing, GAN Wei-hua. Department of Pediatrics, the Second Affiliated
Hospital of Nanjing Medical University, Nanjing 210003, Jiangsu, CHINA

【Abstract】 Objective To explore the clinical value of serum creatine kinase isoenzyme MB (CK-MB) in auxil-
iary examination of children with bronchial pneumonia. Methods A total of 85 patients with bronchial pneumonia ad-
mitted to hospital from January 2015 to August 2015 were randomly enrolled, which were divided into infant and tod-
dler's age group (0~3 years, 57 cases), preschool age group (4~6 years, 22 cases), and school age group (7~14 years, 6
cases). The levels of patients' serum CK-MB on admission were measured, and the changes were evaluated in different
groups. Results Among the 85 patients, there were 49 males and 36 females. The serum CK-MB levels were increased
in 11 patients in the infant and toddler's age group, 1 patient in the preschool age group, and no patient in the school age
group. The level of serum CK-MB was (2.40±1.76) ng/ml in male patients and (2.93±1.96) ng/ml in female patients,
with no statistically significant difference (P>0.05). The level of serum CK-MB was (3.23±1.84) ng/ml in infant and tod-
dler's age group, which were significantly higher than (1.58±1.27) ng/ml in preschool age group and (0.75±0.57) ng/ml
in school age group (P<0.05). Conclusion Serum CK-MB is a classic detection index for clinical diagnosis of myocar-
dial damage. The incidence of myocardial damage in children with bronchial pneumonia is relatively high in infant and
toddler's age group. The serum CK-MB test should be used as routine examination for infants and toddlers with bronchi-
al pneumonia to get better treatment. Meanwhile, the test may not be used as a clinical routine auxiliary examination for
preschool and school age children with bronchial pneumonia.

      【Key words】 Creatine kinase isoenzyme MB (CK-MB); Bronchial pneumonia; Children; Auxiliary examination;
Clinical value
·论 著·
6350.2016.04.013