标题：现代心肺复苏动物模型研究进展

      作者：汤红梅 1 综述 单怡 2 审校    1.上海市奉贤区中医医院急诊科，上海 201499；2.海军军医大学第二附属医院(上海长征医院)急救科，上海 200001

      卷次： 2023年34卷1期

      【摘要】 回顾不同种类动物模型心肺复苏各自的优缺点，简述常用诱导动物心搏骤停的实验方法以及不同实验方法所导致的病理生理改变和心搏骤停造模流程，以及造模成功后各器官功能的改变。为临床不同发病病因所致的心搏骤停以及心搏骤停后人体器官功能改变、组织病理学、生化指标、生物标记物等的变化提供实验依据。
      【关键词】 心搏骤停；心肺复苏；动物模型；造模流程；器官功能
      【中图分类号】 R-332 【文献标识码】 A 【文章编号】 1003—6350（2023）01—0136—05

Advances in modern animal models of cardiopulmonary resuscitation.
TANG Hong-mei 1, SHAN Yi 2. 1. Departmentof Emergency, Fengxian District Hospital of Traditional Chinese Medicine, Shanghai 201499, CHINA; 2. The SecondAffiliated Hospital of Naval Military Medical University (Shanghai Changzheng Hospital), Shanghai 200001, CHINA【Abstract】 The advantages and disadvantages of cardiopulmonary resuscitation (CPR) in different animal mod-els were reviewed. The common expermental methods for inducing cardiac arrest in animals, the pathophysiologicalchanges caused by different experimental methods, the process of cardiac arrest modeling, and the changes of organ func-tion after successful modeling were briefly described, to provide experimental basis for the clinical cardiac arrest causedby different causes and changes of organ function, histopathology, biochemical indicators and biomarkers after cardiacarrest.
      【Key words】 Cardiac arrest; Cardiopulmonary resuscitation; Animal models; Model making process; Organ func-tion　　　·综述·doi:10.3969/j.issn.1003-6350.2023.01.031基金项目：上海市2017年度“科技创新行动计划”实验动物研究领域项目(编号：sh2819083)。第一作者：汤红梅(1981—)，女，主治医师，主要研究方向是临床医学。