标题：右胫骨上段Rosai-Dorfman病一例并文献复习

      作者：陈浩斌 1，2，姚孟宇 1，张驰 1，曾龙辉 1，2，黄文汉 1，雷泽华 1，詹昭颖 1，张余 1    1.广东省人民医院(广东省医学科学院)骨肿瘤，广东 广州 510080；2.南方医科大学第二临床医学院，广东 广州 510515

      卷次： 2023年34卷1期

      【摘要】 报道一例Rosai-Dorfman病的临床特点、影像学表现、病理诊断、鉴别诊断及治疗方法。本例患者临床表现为右胫骨上段肿痛4个月余，影像学提示骨髓炎、单发病灶。手术刮除全部病灶和大量液体冲洗，术后病理检查和免疫组化诊断为结外孤立性罗道病。
      【关键词】 Rosai-Dorfman病；组织细胞增生症；诊断；鉴别诊断；治疗
      【中图分类号】 R557+.4 【文献标识码】 D 【文章编号】 1003—6350（2023）01—0125—05

Rosai-Dorfman disease of the right upper tibia: a case report and literature review.
CHEN Hao-bin 1,2,YAO Meng-yu 1, ZHANG Chi 1, ZENG Long-hui 1,2, HUANG Wen-han 1, LEI Ze-hua 1, ZHAN Zhao-ying 1, ZHANGYu 1. 1. Department of Bone Oncology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,Guangzhou 510080, Guangdong, CHINA; 2. The Second School of Clinical Medicine, Southern Medical University,Guangzhou 510515, Guangdong, CHINA【Abstract】 We report the clinical features, imaging manifestations, pathological diagnosis, differential diagnosis,and treatment of a patient of Rosai-Dorfman disease. The clinical manifestations of this patient were swelling and pain inthe upper segment of the right tibia for more than 4 months, and imaging manifestations showed osteomyelitis and a sin-gle lesion. Surgical curettage and a large amount of fluid flushing were performed. The patient was diagnosed by postop-erative pathological examination and immunohistochemistry as extranodal solitary Rosai-Dorfman disease.
      【Key words】 Rosai-Dorfman disease; Histiocytosis; Diagnosis; Differential diagnosis; Treatment　　　·个案报道·doi:10.3969/j.issn.1003-6350.2023.01.029基金项目：国家自然科学基金(编号：81972126)。第一作者：陈浩斌(1995—)，男，住院医师，主要研究方向为骨肿瘤。