标题：高分辨CT影像学特征对孤立性肺结节良恶性的鉴别诊断效能

      作者：李红英，胡鑫，宋瑞祥    汉中市人民医院放射科，陕西 汉中 723000

      卷次： 2022年33卷19期

      【摘要】 目的 探讨高分辨电子计算机断层扫描(HRCT)影像学特征对孤立性肺结节(SPN)良恶性的鉴别诊断效能。方法 回顾性分析2018年1月至2020年 12月间汉中市人民医院收治的94例SPN患者的临床及影像资料。所有患者均接受HRCT检查。比较恶性SPN (64例)与良性SPN (30例)的影像学特征，以病理检查结果为金标准，评估HRCT诊断SPN良恶性的效能。结果 恶性SPN的分叶征、毛刺征、血管集束征、胸膜凹陷征检出率分别为70.31%、57.81%、32.81%、42.88%，明显高于良性SPN的13.33%、13.33%、6.67%、16.67%，而恶性SPN的卫星灶检出率为 6.25%，明显低于良性 SPN的 30.00%，差异均有统计学意义(P<0.05)；HRCT诊断良恶性 SPN的灵敏度81.25%、特异度 86.67%、准确率 82.98%、阳性预测值 92.86%、阴性预测值68.42%。结论 HRCT鉴别诊断良恶性SPN效能较高，影像学特征具有较高参考价值。
      【关键词】 孤立性肺结节；高分辨电子计算机断层扫描；影像学特征；分叶征；毛刺征；血管集束征；胸膜凹陷征
      【中图分类号】 R445 【文献标识码】 A 【文章编号】 1003—6350（2022）19—2540—04

Analysis of high resolution CT imaging features in the differential diagnosis of solitary pulmonary nodules.
LIHong-ying, HU Xin, SONG Rui-xiang. Department of Radiology, Hanzhong People's Hospital, Hanzhong 723000, Shaanxi,CHINA
【Abstract】 Objective To investigate the differential diagnosis of solitary pulmonary nodules (SPN) by highresolution computed tomography (HRCT) imaging features. Methods The clinical and imaging data of 94 patientswith SPN admitted to Hanzhong People's Hospital from January 2018 to December 2020 were retrospectively analyzed.All patients were examined by HRCT. The imaging features of malignant SPN (64 cases) and benign SPN (30 cases)were compared, and the efficacy of HRCT in diagnosing benign and malignant SPN was evaluated using pathologicalfindings as the gold standard. Results The detection rates of lobulation, burr, vascular cluster, and pleural depression ofmalignant SPN were 70.31%, 57.81%, 32.81%, and 42.88%, respectively, which were significantly higher than 13.33%,13.33%, 6.67%, and 16.67% of benign SPN. The detection rate of malignant SPN was 6.25%, which was significantlylower than 30.00% of benign SPN, with statistically significant difference (P<0.05). HRCT showed a sensitivity of81.25%, a specificity of 86.67%, an accuracy of 82.98%, a positive predictive value of 92.86%, and a negative predictive