标题：精细化管理对PIVAS输液质量安全的影响

      作者：王琳，李静，薛锦    西安国际医学中心医院药学部静脉用药调配中心，陕西 西安 710100

      卷次： 2021年32卷24期

      【摘要】 目的 研究精细化管理对静脉用药调配中心(PIVAS)输液质量安全的影响。方法 采取回顾性分析方法，将西安国际医学中心医院2019年9月至2020年8月期间PIVAS实施精细化管理后的处方96张纳入研究组，2018年9月至2019年8月实施精细化管理前的处方96张纳入对照组。比较两组配制间的灭菌合格率、处方的各项质量指标、PIVAS差错事件发生率。结果 研究组处方的生物安全柜表面、水平层流台表面、小型物体表面、空气沉降、工作人员手部的灭菌合格率明显高于对照组，差异均具有统计学意义(P<0.05)；研究组处方的合理数、药物配置正确数分别为91.67%、96.88%，明显高于对照组的81.25%、89.58%，差异均具有统计学意义(P<0.05)；研究组处方的药物不良反应率为1.04%，明显低于对照组的7.29%，差异具有统计学意义(P<0.05)；研究组处方的PIVAS差错事件总发生率为3.13%，明显低于对照组的10.42%，差异具有统计学意义(P<0.05)。结论 将精细化管理应于PIVAS中可减少差错事件的发生率，保证输液安全，降低医疗纠纷，值得临床推广应用。
      【关键词】 静脉用药调配中心；差错事件；灭菌合格率；输液质量安全；精细化管理
      【中图分类号】 R197.39 【文献标识码】 A 【文章编号】 1003—6350（2021）24—3242—03

Effect of refined management on the quality and safety of PIVAS infusion.
WANG Lin, LI Jing, XUE Jin. IntravenousAdmixture Services, Department of Pharmacy, Xi'an International Medical Center Hospital, Xi'an 710100, Shaanxi, CHINA
【Abstract】 Objective To study the effects of refined management on the quality and safety of infusion in thePharmacy Intravenous Admixture Services (PIVAS). Methods Adopting a retrospective analysis method, the 96 pre-scriptions after the implementation of refined management on PIVAS from September 2019 to August 2020 in Xi'an In-ternational Medical Center Hospital were included in the study group, and 96 prescriptions before the implementation ofrefined management from September 2018 to August 2019 were included in the control group. The sterilization qualifica-tion rate, the quality indicators of the prescription, and the incidence rate of PIVAS error events were compared betweenthe two groups. Results The sterilization qualification rate of the biological safety cabinet surface, the horizontal lami-nar flow table surface, the small object surface, the air sedimentation, and the staff hands prescribed by the study groupwas significantly higher than those of the control group, with statistically significant differences (P<0.05). The reason-able number of prescriptions and the correct number of medications in the study group were 91.67% and 96.88%, respec-tively, which were significantly higher than corresponding 81.25% and 89.58% in the control group, with statistically sig-nificant differences (P<0.05). The adverse drug reaction rate prescribed by the study group was 1.04%, which was signif-icantly lower than 7.29% of the control group (P<0.05). The total incidence of PIVAS error events in the study groupwas 3.13%, which was significantly lower than 10.42% in the control group (P<0.05). Conclusion Applying refinedmanagement to PIVAS can reduce the incidence of error events, ensure the safety of infusion quality, reduce medical dis-putes, and is worthy of clinical application.
      【Key words】 Pharmacy intravenous admixture services; Error event; Sterilization qualification rate; Infusionquality and safety; Refined management·短篇论著·doi:10.3969/j.issn.1003-6350.2021.24.032基金项目：陕西省重点研发项目(编号：S2020-YF-ZDCXL-ZDLSF-0154)