标题：T4期胃癌患者行腹腔镜根治术后远期预后的影响因素

      作者：温陈，遆军锋，张小云    神木市医院肝胆外科，陕西 神木 719300

      卷次： 2021年32卷23期

      【摘要】 目的 研究T4期胃癌患者腹腔镜根治术后远期预后的影响因素。方法 回顾性分析2016年1月至2017年12月神木市医院收治的50例行腹腔镜根治术治疗的T4期胃癌患者的临床资料。所有患者均行腹腔镜根治术治疗，统计患者一般资料，分析患者随访期间预后情况，采用多因素Logistic回归分析法分析T4期胃癌患者腹腔镜根治术后远期预后的独立影响因素。结果 50例患者随访期间，无事件生存 31例，占 62.00%，复发 5例，占 10.00%，死亡 14例，占 28.00%；单因素分析结果显示，T4期胃癌患者腹腔镜根治术后远期预后与肿瘤大小、肿瘤N分期、淋巴结转移及血小板计数有明显相关性(P<0.05)；多因素 Logistic回归分析显示，淋巴结转移(OR=1.269，95%CI=1.136~1.547)及血小板计数(OR=3.927，95%CI=1.537~2.658)是T4期胃癌患者腹腔镜根治术后远期预后的独立影响因素(P<0.05)。结论 淋巴结转移及血小板计数是T4期胃癌患者腹腔镜根治术后远期预后的独立影响因素。
      【关键词】 胃癌；腹腔镜根治术；预后；影响因素；多因素Logistic回归分析
      【中图分类号】 R735.2 【文献标识码】 A 【文章编号】 1003—6350（2021）23—3076—03

Influencing factors of long-term prognosis of T4 gastric cancer patients after laparoscopic radical operation.
WENChen, XI Jun-feng, ZHANG Xiao-yun. Department of Hepatobiliary Surgery, Shenmu Hospital, Shenmu 719300, Shaanxi,CHINA
【Abstract】 Objective To study the influencing factors of long-term prognosis in patients with T4 gastric cancerafter laparoscopic radical operation. Methods The clinical data of 50 patients with T4 gastric cancer treated by laparo-scopic radical gastrectomy in Shenmu Hospital from January 2016 to December 2017 were analyzed retrospectively. Allpatients were treated with laparoscopic radical surgery, and the general data of patients were analyzed. The prognosis ofpatients during follow-up was analyzed, and the independent influencing factors of long-term prognosis of T4 gastric can-cer patients were analyzed by multivariate logistic regression analysis. Results During the follow-up period, 31 of the50 patients (62.00%) survived (event-free survival), 5 had recurrence (10.00%), and 14 died (28.00%). Univariate analy-sis showed that long-term prognosis of patients with T4 stage gastric cancer after laparoscopic radical resection was sig-nificantly correlated with tumor size, tumor N stage, lymph node metastasis, and platelet count (P<0.05). Multivariate lo-gistic regression analysis showed that lymph node metastasis (OR=1.269, 95% CI=1.136 to 1.547) and platelet count(OR=3.927, 95%CI=1.537 to 2.658) were independent factors for the long-term prognosis of T4 gastric cancer patientsafter laparoscopic radical surgery. Conclusion Lymph node metastasis and platelet count were independent factors in-fluencing the long-term prognosis of patients with T4 gastric cancer after laparoscopic surgery.
      【Key words】 Gastric cancer; Laparoscopic radical operation; Prognosis; Influence factor; Multivariate logistic re-gression analysis