标题：急性ST段抬高型心肌梗死患者PCI预后影响因素的研究进展

      作者：李雪 1，陈燕宏 3 综述 赵中江 1，2，邓哲 1，3 审校    1.广东医科大学，广东 湛江 524000；2.深圳市第二人民医院门诊部，广东 深圳 518035；3.深圳大学附属第一医院（深圳市第二人民医院）急诊科，广东 深圳 518035

      卷次： 2021年32卷1期

      【摘要】 ST段抬高型心肌梗死(STEMI)是常见急性心肌梗死分型，发病率及死亡率高。目前急性期的ST段抬高型心肌梗死的救治原则是在最短的血流灌注时间内迅速恢复冠状动脉的有效血流和灌注，直接进行经皮冠状动脉介入治疗(PCI)为STEMI急性期的首选治疗方案，其能及时地开放与梗死相关的罪犯动脉，有效恢复血流，且创伤较小、患者康复快。然而，STEMI患者在接受直接PCI治疗后，仍有部分患者预后不佳。其中“吸烟者悖论”对STEMI患者预后影响仍有较大争议，而许多研究已经证实远隔缺血处理(RIC)的积极作用。本文主要根据近年来国内外关于公认或仍有争议的STEMI患者行直接PCI的预后影响因素的研究进展做一综述。
      【关键词】 急性ST段抬高型心肌梗死；经皮冠状动脉介入治疗；吸烟者悖论；远隔缺血处理；预后
      【中图分类号】 R542.2+2 【文献标识码】 A 【文章编号】 1003—6350（2021）01—0107—05

Research progress on the influencing factors of direct PCI prognosis in patients with acute ST-segment elevationmyocardial infarction.
LI Xue 1, CHEN Yan-hong 3, ZHAO Zhong-jiang 1,2, DENG Zhe 1,3. 1.Guangdong MedicalUniversity, Zhanjiang 524000, Guangdong, CHINA; 2. Department of Outpatient, Shenzhen Second People’s Hospital,Shenzhen 518035, Guangdong, CHINA; 3. Department of Emergency Medicine, the First Affiliated Hospital of ShenzhenUniversity/Shenzhen Second People's Hospital, Shenzhen 518035, Guangdong, CHINA【Abstract】 ST-segment elevation myocardial infarction (STEMI) is the common classification of acute myocar-dial infarction with high morbidity and mortality. The current treatment principle of ST-segment elevation myocardial in-farction in the acute phase is to quickly restore the effective blood flow and perfusion of the coronary arteries in theshortest blood perfusion time. Direct percutaneous coronary intervention (PCI) is the prior measure for the acute phaseof STEMI, which can reopen the culprit arteries in time, restore blood flow effectively and has less injury with faster re-covery. However, after receiving direct PCI treatment, some patients with STEMI still have poor prognosis. The influ-·综述·doi:10.3969/j.issn.1003-6350.2021.01.030