标题：无症状脑梗死的事件相关电位N400的研究

      作者：危 薇，何传兵，董南丁，徐志彬
    （泸州医学院附属医院神经内科脑电图室，四川 泸州 646000）

      卷次： 2014年25卷2期

      【摘要】 目的 探讨无症状脑梗死 (Silent cerebral infarction，SCI)患者的事件相关电位 (Event-related
potential，ERP)N400的变化，分析SCI患者的语言功能损害特点。方法 收集SCI患者（SCI组）和健康成人(对照
组）各82例，分别进行N400检测，将其结果进行比较分析。结果 与对照组比较，SCI组的N400潜伏期延长(P<
0.01)，波幅降低(P<0.05)。结论 SCI患者虽然无明显临床症状，但语言功能有一定程度的减退。

      【关键词】 无症状脑梗死；N400；事件相关电位

      【中图分类号】 R743.33 【文献标识码】 A 【文章编号】 1003—6350（2014）02—0201—02


Eevent-related potentials N400 in patients with silent cerebral infarction.
WEI Wei, HE Chuan-bing, DONG
Nan-ding, XU Zhi-bin. EEG Room, Department of Neurology, the Affiliated Hospital to Luzhou Medical College, Luzhou
646000, Sichuan, CHINA

【Abstract】 Objective To explore the change of event-related potentials (ERP) N400 in patients with silent
cerebral infarction (SCI) and analyze the features of their language function impairment. Methods Eighty-two SCI
patients (SCI group) and 82 normal health controls (control group) were selected. They were tested by N400 and the re-
sults were compared and analyzed. Results Compared with that in control group, the latency of N400 was longer (P<
0.01) and the amplitude was lower (P<0.05) in SCI group. Conclusion Although there are no significant clinical
symptoms in patients with SCI, their language function has been impaired to some extent.