标题：肥胖与缺血性卒中相关性研究进展

      作者：秦涛 综述 刘安祥，张骏 审校    遵义医科大学附属医院神经内科，贵州 遵义 563000

      卷次： 2020年31卷16期

      【摘要】 全球脑卒中的患者在逐年增加，其中缺血性卒中约占脑卒中患者总数的70%，具有高发病率、高致死率、高致残率等特点，同时也是导致全球血管性疾病及致残的常见原因，严重的威胁着人类的生命健康和影响社会经济的发展。肥胖作为缺血性卒中可控性危险因素，控制肥胖能有效降低缺血性卒中的发生率。本文将对肥胖的定义、流行趋势，以及肥胖与缺血性卒中的相关可能机制进行综述。
      【关键词】 缺血性卒中；肥胖；脂肪因子；瘦素；脂联素；内脂素；抵抗素
      【中图分类号】 R743.3 【文献标识码】 A 【文章编号】 1003—6350（2020）16—2126—03

Research progress on the correlation between obesity and ischemic stroke.
QIN Tao, LIU An-xiang, ZHANG Jun.Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou, CHINA【Abstract】 The number of stroke patients in the world is increasing year by year, among which ischemic strokeaccounts for about 70% of the total number of stroke patients. It is characterized by high morbidity, high lethality, andhigh disability. It is also a common cause of vascular diseases and disability worldwide, which seriously threatens humanlife and health and affects the development of social economies. Obesity is a controllable risk factor for ischemic stroke,and controlling obesity can effectively reduce the incidence of ischemic stroke. This article will review the definition,prevalence, and the possible mechanisms of obesity and ischemic stroke.
      【Key words】 Cerebral ischemic stroke; Obesity; Adipokines; Leptin; Adiponectin; Visfatin; Resistin·综述·doi:10.3969/j.issn.1003-6350.2020.16.024基金项目：国家自然科学基金(编号：81760225)