标题：血小板微粒与缺血性脑卒中诊疗的研究进展

      作者：李庆运，曾俊玲 综述 陈煜森审校    广东医科大学附属医院神经内科，广东 湛江 524001

      卷次： 2020年31卷8期

      【摘要】 血小板微粒(PMP)是血小板激活或自身凋亡释放的直径在0.1~1.0 μm的颗粒样物质，具有促进血栓形成、血管新生、参与炎症调节等多种特性，在缺血性脑卒中诊断、治疗及预测预后方面具有巨大潜力。该文旨在探讨PMP与缺血性脑卒中相关病理生理机制、标志物、治疗方面关系并据此作一阐述。
      【关键词】 缺血性脑卒中；神经治疗；血小板微粒；预后；炎症反应
      【中图分类号】 R73.3 【文献标识码】 A 【文章编号】 1003—6350（2020）08—1041—05

Advances in research on the diagnosis and treatment of platelet microparticles and ischemic stroke.
LI Qing-yun,ZENG Jun-ling, CHEN Yu-sen. Department of Neurology, the Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001, Guangdong, CHINA【Abstract】 Platelet-derived microparticles (PMPs) are particle-like substances with a diameter of 0.1-1.0 μm re-leased by platelet activation or auto-apoptosis. They have various characteristics such as promoting thrombosis, angio-genesis, and participating in inflammatory regulation. PMPs have great potential in the diagnosis, treatment, and progno-sis of ischemic stroke. This article aims to explore the relationship between PMPs and pathophysiological mechanisms,markers, and treatments related to ischemic stroke.
      【Key words】 Ischemic stroke; Neurotherapy; Platelet-derived microparticles (PMPs); Prognosis; Inflammation·综述·doi:10.3969/j.issn.1003-6350.2020.08.027基金项目：广东省医学科研基金(编号：B2018048)；广东省湛江市科技攻关计划项目(编号：2018B01012)