标题：急性脑卒中急诊头颈联合CTA对肾功能的影响

      作者：黄丽娜 1，汤建军 2    上海德济医院急诊科 1、神经内科 2，上海 200331

      卷次： 2020年31卷4期

      【摘要】 目的 研究急性脑卒中患者应用急诊头颈联合CT血管造影(CTA)对于患者肾功能的影响。方法 回顾性分析上海德济医院2018年1月至2019年6月收治的78例行急诊头颈联合CTA检查的急性脑卒中患者的临床资料，其中单纯高血压38例，单纯糖尿病25例，糖尿病合并高血压15例，观察患者检查前后的肾小球滤过率的估算值(eGFR)、血浆胱抑素C (CysC)以及血清肌酐(Cre)。结果 78例患者行急诊头颈联合CTA检查前后的CysC[(0.91±0.24) mg/dL vs (0.95±0.26) mg/dL]、Cre [(67.63±17.33) μmol/L vs (68.96±14.93) μmol/L]以及 eGFR [(102.02±23.71) mL/(min·1.73 m2) vs (99.80±20.02) mL/(min·1.73 m2)]指标比较差异均无统计学意义(P>0.05)；糖尿病组、高血压病组以及高血压联合糖尿病组患者行急诊头颈联合CTA检查前后的CysC、Cre及 eGFR指标比较差异均无统计学意义(P>0.05)。结论 基础肾功能正常的患者，合并高血压、糖尿病或者联合高血压糖尿病的患者行急诊头颈联合CTA检查是相对安全的，检查前后CysC、Cre以及eGFR指标无明显变化。
      【关键词】 血浆胱抑素C；肾小球滤过率；急诊头颈联合CTA；血清肌酐；急性脑卒中
      【中图分类号】 R743.3 【文献标识码】 A 【文章编号】 1003—6350（2020）04—0488—03

Effect of emergency head and neck combined with CTA on renal function in acute stroke emergency.
HUANGLi-na 1, TANG Jian-jun 2. Department of Emergency 1, Department of Internal Medicine-Neurology 2, the Deji Hospital ofShanghai, Shanghai 200331, CHINA
【Abstract】 Objective To study the effect of emergency head and neck combined with CT angiography (CTA)on renal function in patients with acute stroke. Methods The clinical data of 78 patients with acute stroke who under-went emergency head and neck combined with CTA from January 2018 to June 2019 in Shanghai Deji Hospital were ret-rospectively analyzed, including 38 cases of simple hypertension, 25 cases of simple diabetes, and 15 cases of diabetescomplicated with hypertension. The estimated glomerular filtration rate (eGFR), plasma cystatin C (CysC), and serumcreatinine (Cre) before and after examination were observed. Results The was no significant difference in the index-es of Cysc, CRE and EGFR before and after emergency head and neck combined with CTA examination in 78 patients(all P>0.05): (0.91±0.24) mg/dL vs (0.95±0.26) mg/dL, (67.63±17.33) μmol/L vs (68.96±14.93) μmol/L, (102.02±23.71) mL/(min·1.73 m2) vs (99.80±20.02) mL/(min·1.73 m2). There was no significant difference in CysC, Cre and eG-FR indexes before and after emergency head and neck combined with CTA examination among the diabetes group, hy-pertension group and hypertension combined diabetes group (all P>0.05). Conclusion Emergency head and neck com-bined with CTA examination is relatively safe for the patients with normal basic renal function and patients with hyper-tension, diabetes or hypertension and diabetes. There is no obvious changes in CysC, Cre and eGFR indexes before andafter examination.
      【Key words】 Plasma Cystatin C (CysC); Glomerular filtration rate (GFR); Emergency head and neck combinedwith CTA; Serum creatinine (Cre); Acute stroke