标题：薄荷醇穴位敷贴防治消化道肿瘤患者围术期口渴疗效观察

      作者：常小兰，刘思兰，奚冰，桂林，陆香红    苏州大学附属第一医院平江院区麻醉手术科，江苏 苏州 215006

      卷次： 2020年31卷4期

      【摘要】 目的 观察薄荷醇穴位敷贴防治消化道肿瘤患者围术期口渴的疗效。方法 将2017年1月至2018年 12月期间苏州大学附属第一医院收治的 120例在全麻下行手术根治术的ASA分级为Ⅰ~Ⅱ级的消化道肿瘤患者采用随机数表法分为对照组(C组，n=60)和实验组(S组，n=60)，患者在术晨 6 h将薄荷醇贴(S组)或者空白胶布(C组)贴于指定穴位处(照海、水泉和廉泉)。分别记录两组患者入手术室(T1)、出麻醉恢复室(PACU) (T2)、术后 6 h (T3)、术后 12 h (T4)和术后 24 h (T5)的口渴评分，并计算口渴发生率，同时测量拔除气管导管时从患者咽喉部吸引出的痰液量以及痰液的 pH值。结果 从 T1开始至 T5时，C组患者的口渴评分明显高于 S组，组间比较差异均有统计学意义(P<0.05)；从 T2开始至 T5，C组患者的口渴评分明显高于 T1时，组内比较差异均有统计学意义(P<0.05)；从 T3开始至 T5时，S组患者口渴评分明显高于 T1时，组内比较差异均具有统计学意义(P<0.05)。从 T1开始至 T5时，C组患者的口渴发生率明显高于 S组，组间比较差异均具有统计学意义 (P<0.05)；从 T3开始至 T5时，C组患者的口渴发生率显著降低，组内比较差异具有统计学意义(P<0.05)；T4和 T5时 S组患者的口渴发生率显著降低，组内比较差异有统计学意义(P<0.05)。两组患者拔管时有痰率、痰液量和痰液的 pH值比较差异均无统计学意义(P>0.05)。结论 术晨即给予患者薄荷醇穴位贴敷可有效降低消化道肿瘤患者围术期口渴的发生率，并显著降低其口渴的严重程度，这种安全、便捷、有效且持久的防治口渴的方法值得临床推广应用。
      【关键词】 薄荷醇贴；消化道肿瘤；围术期；口渴；疗效
      【中图分类号】 R735 【文献标识码】 A 【文章编号】 1003—6350（2020）04—0442—04

Effect of menthol acupoint application on prevention and treatment of perioperative thirst in patients withgastrointestinal cancer.
CHANG Xiao-lan, LIU Si-lan, XI Bing, GUI Lin, LU Xiang-hong. Department of Anesthesiology,Pingjiang Branch of the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, CHINA
【Abstract】 Objective To investigate the effect of menthol acupoint application on prevention and treatment ofperioperative thirst in patients with gastrointestinal cancer. Methods From January 2017 to December 2018, 120 gas-trointestinal cancer patients with ASA grade Ⅰ~Ⅱwho underwent general anesthesia were divided into control group(group C, n=60) and experimental group (group S, n=60) according to the random number table method. At 6 o'clock inthe morning before surgery, the patient applied menthol acupoint tape (group S) or blank tape (group C) to the designatedacupoints (Zhaohai, Shuiquan, and Lianquan). The thirst scores of two groups were recorded when the patients entered theoperating room (T1), when they left the post anesthesia care unit (PACU) (T2), at 6 h (T3), 12 h (T4), and 24 h (T5) aftersurgery, and the incidence of thirst was calculated. At the same time, the amount and pH of the sputum drawn from the pa-tient's throat were measured when the tracheal tube was removed. Results From T1 to T5, the thirst score was signifi-cantly higher in group C than in group S (P<0.05). From T2 to T5, the thirst score of group C was significantly higherthan that at T1 (P<0.05). From T3 to T5, the thirst score of group S was significantly higher than that at T1 (P<0.05).From T1 to T5, the incidence of thirst was significantly higher in group C than in group S (P<0.05). From T3 to T5, theincidence of thirst in group C was significantly reduced (P<0.05). The incidence of thirst in group S was significantly re-duced at T4 and T5 (P<0.05). There was no significant difference in the production rate, amount, and pH of sputum be-tween the two groups during extubation (P>0.05). Conclusion Applying a menthol acupoint application to patient ear-ly in the morning before surgery can effectively reduce the incidence of perioperative thirst and significantly reduce theseverity of thirst in patients with gastrointestinal cancer. This safe, convenient, effective and durable method for the pre-vention and treatment of thirst is worthy of clinical promotion.
      【Key words】 Menthol acupoint application; Gastrointestinal cancer; Perioperative period; Thirst; Curative effect