标题：63例特发性膜性肾病预后分析

      作者：刘泽兵，杨林，李国刚，高琦    三峡大学第一临床医学院肾病内科，湖北 宜昌 443000

      卷次： 2019年30卷22期

      【摘要】 目的 分析特发性膜性肾病(IMN)患者经规范治疗的预后。方法 选取三峡大学第一临床医学院2013—2016年经肾穿刺活检组织病理诊断为 IMN的63例患者，以内生肌酐清除率(Ccr)下降1倍或进入终末期肾病(ESRD)或死亡作为随访终点，观察患者经过规范治疗后1年、2年、3年的疗效。结果 所有患者经过治疗后，1年、2年、3年的总缓解率分别为85.7%、81.0%、87.3%；3年肾脏生存率为95.2%。结论 IMN患者经规范治疗后的总缓解率和肾脏生存率均较好，且短期预后良好。
      【关键词】 膜性肾病；特发性膜性肾病；肾病综合征；预后；终末期肾病
      【中图分类号】 R692 【文献标识码】 A 【文章编号】 1003—6350（2019）22—2961—03

Prognosis analysis of 63 cases of idiopathic membranous nephropathy.
LIU Ze-bing, YANG Lin, LI Guo-gang, GAOQi. Department of Nephropathy, the First Clinical Medical College of China Three Gorges University, Yichang 443000,Hubei, CHINA
【Abstract】 Objective To analyze the prognosis of idiopathic membranous nephropathy (IMN) after standardtreatment. Methods Sixty-three patients diagnosed by renal biopsy as IMN from 2013 to 2016 in the First ClinicalMedical College of Three Gorges University were selected. The end-point of follow-up was a decrease of endogenouscreatinine clearance (Ccr) to a half or an end-stage renal disease (ESRD) or death. The curative effect at 1 year, 2 years,and 3 years after standard treatment was observed. Results After treatment, the total remission rates of all patients were85.7%, 81.0% and 87.3% at 1 year, 2 years, and 3 years after standard treatment, respectively. The 3-year renal survivalrate was 95.2%. Conclusion The overall remission rate and renal survival rate of IMN patients were improved afterstandard treatment, and the short-term prognosis was good.
      【Key words】 Membranous nephropathy; Idiopathic membranous nephropathy; Nephrotic syndrome; Prognosis;End-stage renal disease·短篇论著·doi:10.3969/j.issn.1003-6350.2019.22.031基金项目：湖北省宜昌市医疗卫生科研资助项目(编号：A19-301-04)