标题：子宫颈扩张球囊在足月妊娠引产中的应用及其对产妇应激反应的影响

      作者：任虹，曹玲玲    复旦大学附属华山北院宝山分院妇产科，上海 200431

      卷次： 2019年30卷16期

      【摘要】 目的 探讨子宫颈扩张球囊在足月妊娠引产中的应用及其对产妇应激反应的影响。方法 选择2016年5月至2018年4月复旦大学附属华山北院宝山分院接诊的足月妊娠引产患者82例作为对象，按随机数表法分为对照组和观察组，每组41例。对照组给予控释地诺前列酮栓引产，观察组采用子宫颈扩张球囊引产，比较两组产妇的Bishop评分、第一产程、分娩后血清皮质醇(CORT)、儿茶酚胺(CA)、血浆谷氨酸(GLU)水平以及并发症发生情况。结果 观察组和对照组产妇促宫颈成熟后的Bishop评分[(7.82±1.09)分 vs (7.69±0.89)分]和第一产程[(7.01±0.73) h vs (8.85±0.95) h]比较，差异均无统计学意义(P>0.05)；观察组产妇分娩后的CORT、CA和GLU水平分别为(44.39±1.05) μg/L、(143.29±21.43) ng/L、(5.32±0.87) mmol/L，均明显低于对照组的(72.12±1.28) μg/L、(203.29±23.69) ng/L、(7.03±0.91) mmol/L，差异均有显著统计学意义(P<0.01)；观察组产妇产后子宫乏力和产后出血率分别为2.44%、0，均明显低于对照组的9.76%、12.20%，差异均有统计学意义(P<0.05)。结论 子宫颈扩张球囊用于足月妊娠引产中能降低产妇的分娩应激反应，降低宫缩乏力及产后出血等并发症发生率，值得推广应用。
      【关键词】 子宫颈扩张球囊；欣普贝生；足月妊娠引产；应激反应；Bishop评分；并发症
      【中图分类号】 R169.42 【文献标识码】 A 【文章编号】 1003—6350（2019）16—2092—03

Application of cervical dilatation balloon in induction of labor in term pregnancy and its effect on maternal stressresponse.
REN Hong, CAO Ling-ling. Department of Obstetrics and Gynecology, Baoshan Branch of Huashan North Courtof Fudan University, Shanghai 200431, CHINA
【Abstract】 Objective To investigate the application of cervical dilatation balloon in induction of labor in termpregnancy and its effect on maternal stress response. Methods Eighty-two patients with term pregnancy induced byFushan Branch of Huashan North Hospital Affiliated to Fudan University from April 2016 to April 2018 were selectedand divided into the control group and observation group according to random number table methods, with 41 cases ineach group. The control group was given controlled release of dinoprostone suppository, and the observation group wasinduced by cervical dilatation balloon. The Bishop score, serum cortisol (CORT), catecholamine (CA), plasma glutamate(GLU) levels, and complications after delivery of the two group were compared. Results There was no significant dif-ference between the observation group and control group in the Bishop scores after cervical ripeningand the first stage:(7.82±1.09) vs (7.69±0.89), (7.01±0.73) h vs (8.85±0.95) h, P>0.05; the CORT, CA, GLU levels of the observation groupwere (44.39±1.05) μg/L, (143.29±21.43) ng/L, (5.32±0.87) mmol/L, respectively, which were significantly lower thancorresponding (72.12±1.28) μg/L, (203.29±23.69) ng/L, (7.03±0.91) mmol/L of the control group (all P<0.01); the post-partum uterine weakness and postpartum hemorrhage rate in the observation group were 2.44% and 0, respectively,which were significantly lower than 9.76% and 12.20% of the control group of (P<0.05). Conclusion Cervical dilata-tion balloon can reduce the maternal labor stress response and the incidence of complications such as uterine atony andpostpartum hemorrhage. It is worthy of popularization and application.
      【Key words】 Cervical dilatation balloon; Shin pubson; Induction of labor for full-term pregnancy; Stress reac-tion; Bishop score; Complication