标题：酒精依赖与双相情感障碍共病患者的临床特征及生活质量调查

      作者：吕园园，陈宝嫦，许律琴    江门市第三人民医院心理科，广东 江门 529000

      卷次： 2019年30卷8期

      【摘要】 目的 探讨酒精依赖与双相情感障碍共病患者的临床特征，并调查其生活质量和负性情绪。方法 收集2017年3月到2018年12月在江门市第三人民医院诊治的30例酒精依赖与双相情感障碍共病患者纳入观察组，并选择同期30例健康体检者纳入对照组，比较两组研究对象的临床资料，同时使用SF-36量表调查两组研究对象的生活质量，使用 Zung焦虑(SAS)和抑郁自评量表(SDS)评价其焦虑抑郁情况。结果 观察组患者中男性占93.3%，明显高于对照组的63.3%，受教育年限为(8.2±2.8)年，明显低于对照组的(10.3±3.1)年，已婚占56.7%，在职占53.3%，均明显低于对照组的86.7%和80.0%，差异均有统计学意义(P<0.05)；观察组患者SF-36量表中的生理功能、活力、生理职能、情感职能、躯体疼痛、总体健康、精神健康及社会功能评分均明显低于对照组，差异均有统计学意义(P<0.05)；观察组患者的 SAS、SDS评分分别为(48.9±3.4)分、(47.2±6.8)分，均明显高于对照组的(40.3±4.1)分、(41.2±7.4)分，差异均有统计学意义(P<0.05)。结论 酒精依赖与双相情感障碍共病患者以男性为主，且受教育水平相对较低，婚姻关系及就业情况相对不理想，患者的生活质量显著降低且负性情感突出。
      【关键词】 酒精依赖；双相情感障碍；共病；生活质量；临床特征
      【中图分类号】 R749.6+2 【文献标识码】 D 【文章编号】 1003—6350（2019）08—1076—03

Clinical characteristics and quality of life of patients with comorbid alcohol dependence and bipolar disorder.
LVYuan-yuan, CHEN Bao-chang, XU Lv-qin. Department of Psychology, Jiangmen Third People's Hospital, Jiangmen529000, Guangdong, CHINA
【Abstract】 Objective To investigate the clinical characteristics and quality of life of patients with comorbid al-cohol dependence and bipolar disorder, and to investigate their negative emotions. Methods Thirty patients with alco-hol dependence and bipolar disorder treated in Jiangmen Third People's Hospital from March 2017 to December 2018were included into the observation group, and 30 healthy people were selected as the control group. The clinical data ofthe two groups were compared. Meanwhile, SF-36 scale was used to investigate their quality of life, and self-ratinganxiety scale (SAS) and self-rating depression scale (SDS) were used to evaluate anxiety and depression in bothgroups. Results The proportion of males in the observation group was higher than that in the control group (93.3% and63.3%, P<0.05). The educational years in the observation group were (8.2±2.8) years, which was shorter than (10.3±3.1) years inthe control group, and the proportions of married persons and in-service persons were 56.7% and 53.3%, significantlylower than 86.7% and 80.0% in the control group (P<0.05). The SF-36 scale scores, including physiological function(PF), vitality (VT), physiological function (RP), emotional function (RE), body pain (BP), general health (GH), mentalhealth (MH), and social function (SF), of the observation group were significantly lower than those in the control group(P<0.05). The SAS and SDS scores of the observation group were (48.9 ± 3.4), (47.2 ± 6.8), significantly higher than(40.3±4.1), (41.2±7.4) of the control group (P<0.05). Conclusion Patients with alcohol dependence complicating bipo-lar disorder are predominantly males, and their education level is relatively low, with relatively unsatisfactory marital re-lationship and employment situation, significantly reduced quality of life, and prominent negative emotions.
      【Key words】 Alcohol dependence; Bipolar disorder; Comorbidity; Quality of life; Clinical characteristics·调查研究·doi:10.3969/j.issn.1003-6350.2019.08.035