标题：不同经皮冠状动脉介入治疗时间对急性冠状动脉综合征患者预后的影响

      作者：刘宝堂，敬永强，郭荫飞    略阳县人民医院心血管内科，陕西 汉中 724300

      卷次： 2019年30卷8期

      【摘要】 目的 研究不同的经皮冠状动脉介入治疗(PCI)时间对冠状动脉综合征(ACS)患者预后的影响。方法 选取汉中市略阳县人民医院心血管内科2013年6月至2017年6月收治且行PCI治疗的70例ACS患者为研究对象。按照介入时间不同，将患者分为A、B、C三组。A组PCI介入治疗时间为发病后<24 h，B组PCI介入治疗时间为发病后24~72 h，C组PCI介入治疗时间为发病72 h后。比较三组患者的PCI成功率、术后血流TIMI分级改善率、术后胸痛的缓解情况，以及术中、术后并发症的发生率和住院天数。结果 术后，A、B、C三组患者在PCI成功率、术后血流TIMI分级改善率和术后胸痛率方面比较差异无统计学意义(P>0.05)。术中，A组患者的不良心血管发生率为24.0%，明显高于B组的12.0%和C组的10.0%，差异有统计学意义(P<0.05)。A、B、C三组患者术后不良心血管发生率分别为12.0%、8.0%和10.0%，差异无统计学意义(P>0.05)；C组患者的住院天数为(22.6±2.9) d，明显长于A组的(17±2.7) d和B组的(14±3.9) d，差异有统计学意义(P<0.05)。结论 冠状动脉综合征患者在发病后24~72 h内进行PCI介入治疗，更加安全高效，值得在临床广泛推广。
      【关键词】 急性冠状动脉综合征；经皮冠状动脉介入治疗；不良心血管事件；疗效；预后
      【中图分类号】 R541.4 【文献标识码】 A 【文章编号】 1003—6350（2019）08—0970—03

Effect of different percutaneous coronary intervention time on prognosis of patients with acute coronarysyndrome.
LIU Bao-tang, JING Yong-qiang, GUO Yin-fei. Department of Cardiovascular Medicine, Lueyang People'sHospital, Hanzhong 724300, Shaanxi, CHINA
【Abstract】 Objective To study the effect of different percutaneous coronary intervention (PCI) time on theprognosis of patients with acute coronary syndrome (ACS). Methods A total of 70 patients with ACS were selected asthe subjects, who underwent PCI in the Department of Cardiovascular Medicine at Lueyang People's Hospital from June2013 to June 2017. According to the intervention time, the patients were divided into three groups: A, B and C. The timeof PCI interventional therapy in group A was less than 24 hours after onset, that in group B was 24-72 hours after onset,and that in group C was 72 hours after onset. Comparison of three groups were explored on the change of PCI successrate, graded improvement rate of postoperative blood flow TIMI, postoperative chest pain relief, incidence of intraopera-tive, postoperative complications, hospitalization days. Results After operation, there was no significant difference inPCI success rate, postoperative blood flow TIMI grading improvement rate, and postoperative chest pain rate among thethree groups (P>0.05). During the operation, the incidence of adverse cardiovascular disease in group A was 24.0% ,which was significantly higher than 12.0% in group B and 10.0% in group C (P<0.05). The incidence of adverse cardio-vascular events in patients with A, B, and C was 12.0%, 8.0%, and 10.0%, respectively (P>0.05). The hospitalization dayin group C was (22.6±2.9) d, which was significantly longer than (17±2.7) d in group A and (14±3.9) d in group B (P<0.05). Conclusion Patients with coronary syndrome who undergo percutaneous coronary intervention (PCI) within 24to 72 hours after onset is safer and more effective, which is worthy of widespread promotion in clinical practice.
      【Key words】 Acute coronary syndrome; Percutaneous coronary intervention; Adverse cardiovascular events; Effi-cacy; Prognosis