标题：微创穿刺术治疗基底节区脑出血疗效观察

      作者：王战英 1，夏辉 1，千超 2    (1.延安大学咸阳医院神经内科，陕西 咸阳 712000；2.核工业215医院神经外科，陕西 咸阳 712000)

      卷次： 2018年29卷23期

      【摘要】 目的 比较微创穿刺术与内科保守疗法治疗基底节区脑出血的临床疗效，以为临床上基底节脑出血治疗方案的选择提供依据。方法 选择2014年1月至2017年1月期间延安大学咸阳医院收治的104例基底节脑出血患者为研究对象，根据随机数表法分为观察组与对照组，每组52例，对照组患者给予内科保守治疗，观察组给予微创穿刺术治疗，比较两组患者治疗前及治疗14 d后美国国立卫生研究院卒中量表(NIHSS)评分的变化，并在治疗后3个月时根据格拉斯哥预后评分(GOS)判断患者的近期预后。结果 治疗后14 d，观察组患者的NIHSS评分为(9.14±2.96)分，明显低于对照组的(12.15±4.58)分，差异有统计学意义(P<0.05)；治疗后3个月，观察组患者的优良率为67.31%，明显高于对照组的46.14%，差异有统计学意义(P<0.05)。结论 微创穿刺术治疗基底节区脑出血可以及时有效的清除血肿，明显改善神经功能缺损及近期预后，值得在临床推广应用。
      【关键词】 高血压脑出血；微创穿刺术；基底节区；预后
      【中图分类号】 R743.34 【文献标识码】 A 【文章编号】 1003—6350（2018）23—3312—03

Therapeutic observation of minimally invasive puncture in treatment of basal ganglia cerebral hemorrhage.WANG Zhan-ying 1, XIA Hui 1, QIAN Chao 2.
1. Department of Neurology, Xianyang Hospital of Yan'an University,Xianyang 712000, Shaanxi, CHINA; 2. Department of Neurosurgery, No. 215 Hospital of Shaanxi Nuclear Industry,Xianyang 712000, Shaanxi, CHINA
【Abstract】 Objective To compare the clinical efficacy of minimally invasive puncture and internal conserva-tive therapy in the treatment of basal ganglia cerebral hemorrhage, in order to provide a basis for the choice of treatmentoptions for clinical basal ganglia hemorrhage. Methods A total of 104 patients with basal ganglia hemorrhage treatedin the Xianyang Hospital of Yan'an University during January 2014 and January 2017 were selected as subjects. Accord-ing to the random number table method, they were divided into an observation group and a control group, with 52 casesin each group. Patients in the control group were treated with conservative treatment, and those in the observation groupreceived minimally invasive puncture treatment. The changes in the National Institutes of Health Stroke Scale (NIHSS)scores before and after 14 days of the treatment were compared between the two groups, and the short-term prognosiswas determined according to the Glasgow Outcome Scale (GOS) at 3 months after treatment. Results At 14 days aftertreatment, the NIHSS score in the observation group was (9.14±2.96), which was significantly lower than (12.15±4.58)in the control group, and the difference was statistically significant (P<0.05). At 3 months after treatment, the excellentrate in the observation group was 67.31%, which was significantly higher than 46.14% in the control group (P<0.05).Conclusion Minimally invasive puncture in the treatment of basal ganglia cerebral hemorrhage can be timely and ef-fective in eliminating hematoma, and significantly improve neurological deficits and short-term prognosis, which is wor-thy of clinical application.
      【Key words】 Hypertensive intracerebral hemorrhage; Minimally invasive puncture; Basal ganglia region; Prognosis·论 著·doi:10.3969/j.issn.1003-6350.2018.23.018基金项目：陕西省科学技术研究发展计划基金(编号：2012SF2-02-05)