标题：益气安神膏治疗气虚质失眠疗效观察

      作者：金燕，陈瑞芳，常少琼，刘津    (广州中医药大学第一附属医院治未病科，广东 广州 510405)

      卷次： 2018年29卷22期

      【摘要】 目的 探讨基于“五脏相关”理论的益气安神膏治疗气虚质失眠的疗效。方法 选择广州中医药大学第一附属医院治未病科2017年1月至2018年3月期间收治的72例气虚质失眠患者为研究对象，根据随机数表法分为观察组和对照组，每组36例，对照组予舒乐安定治疗，观察组则应用基于“五脏相关”理论的益气安神膏治疗，每两周为一个疗程，治疗两个疗程。比较两组患者治疗前后匹兹堡睡眠质量指数量表(PSQI)及中医症候评分的变化和临床疗效。结果 治疗后，两组患者的PSQI评分、中医症候评分均较治疗前明显下降，差异均有统计学意义(P<0.05)；但是两组间比较差异均无统计学意义(P>0.05)；治疗后1个月，观察组患者的PSQI评分为(8.22±1.08)分，明显低于对照组的(10.36±1.26)分，中医症候评分为(9.92±1.23)分，明显低于对照组的(12.25±1.38)分，差异均有统计学意义(P<0.05)；观察组患者的治疗总有效率为 83.33%，明显高于对照组的 63.89%，差异有统计学意义(P<0.05)。结论 在“五脏相关”理论指导下，应用益气安神膏治疗气虚质失眠可以有效提高睡眠质量改善临床症状，治疗效果优于舒乐安定。
      【关键词】 失眠；睡眠障碍；五脏相关；气虚；疗效
      【中图分类号】 R256.23 【文献标识码】 A 【文章编号】 1003—6350（2018）22—3126—03

Therapeutic effect of Yiqi Anshen ointment in treating Qi deficiency insomnia.
JIN Yan, CHEN Rui-fang, CHANGShao-qiong, LIU Jin. Department of Preventive Medicine, the First Affiliated Hospital of Guangzhou University of ChineseMedicine, Guangzhou 510405, Guangdong, CHINA
【Abstract】 Objective To explore the effect of Yiqi Anshen ointment in treating Qi deficiency insomnia basedon the theory of "five viscera correlation". Methods A total of 72 patients with Qi deficiency insomnia admitted to theDepartment of Preventive Medicine, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, fromJanuary 2017 to March 2018 were selected and divided into an observation group and a control group according to therandom number table method, each group with 36 cases. The control group was treated with estazolam, and the observa-tion group was treated with Yi Qi Anshen ointment based on the "Five viscera correlation" theory; every 2 weeks was acourse of treatment and the treatment lasted 2 courses. Comparison was explored on the change of Pittsburgh Sleep Qual-ity Index (PSQI) and TCM symptom scores before and after treatment in the two groups of patients and clinical efficacy.Results After treatment, the PSQI scores and TCM symptom scores in both groups were significantly lower than thosebefore treatment, and the difference was statistically significant (P<0.05); but there was no significant difference be-tween the two groups (P>0.05). One month after treatment, the PSQI score of the observation group was (8.22±1.08),which was significantly lower than (10.36±1.26) of the control group; and the TCM symptom score in the observationgroup was (9.92±1.23), which was significantly lower than (12.25±1.38) in the control group; and the differences werestatistically significant (P<0.05). The total effective rate in the observation group was 83.33% , significantlyhigher than that in the control group (63.89%), and the difference was statistically significant (P<0.05). Conclusion Un-der the guidance of the "Five viscera correlation" theory, the application of Yiqi Anshen ointment in the treatment of Qideficiency insomnia can effectively improve the quality of sleep and improve clinical symptoms. The therapeutic effectis better than that of estazolam.
      【Key words】 Insomnia; Sleep disorders; Five viscera-related; Qi deficiency; Therapeutic effect·论 著·doi:10.3969/j.issn.1003-6350.2018.22.006