标题：心力衰竭儿童预后的影响因素分析

      作者：邱梅冰，金伶    (柳州市人民医院儿科，广西 柳州 545006)

      卷次： 2018年29卷21期

      【摘要】 目的 探讨影响儿童心力衰竭预后的因素。方法 对2016年1月至2018年1月在柳州市人民医院儿科住院的 133例心力衰竭患儿根据改良 Ross评分进行分级，对患儿的血液学指标 N-端脑利钠肽前体(NT-proBNP)、红细胞分布宽度(RDW)、高敏C反应蛋白(hsCRP)、白蛋白(ALB)、钠离子(Na+)、钾离子(K+)进行单因素分析，然后用Logistic回归进行多因素综合分析。结果 133例心衰患儿按预后分为死亡组21例及好转组112例，按改良Ross评分分为轻度心衰组(3~6分) 68例、中度心衰组(7~9分) 39例、重度心衰组(10~12分) 26例，其中轻度心衰组死亡率为2.9% (2/68例)，中度心衰组为15.3% (6/39例)，重度心衰组为50.0% (13/26例)。经单因素分析结果显示，RDW、hsCRP、ALB对心衰患儿的预后有影响(P<0.05)，再经Logistic回归进行多因素综合分析，结果显示RDW、ALB因素是影响心衰患儿预后的高危因素(P<0.05)。结论 RDW、ALB是影响心力衰竭患儿预后的危险因素。
      【关键词】 儿童；心力衰竭；回归分析；预后
      【中图分类号】 R725.6 【文献标识码】 A 【文章编号】 1003—6350（2018）21—2980—04

Analysis of influencing factors of prognosis in children with heart failure.
QIU Mei-bing, JIN Ling. Department ofPediatrics, Liuzhou People’s Hospital, Liuzhou 545006, Guangxi, CHINA
【Abstract】 Objective To explore the factors affecting the prognosis of children with heart failure. Methods Atotal of 133 children with heart failure admitted to the Department of Pediatrics at the Liuzhou People's Hospital from Janu-ary 2016 to January 2018 were graded according to the modified Ross score. A single factor analysis was performed onthe hematological indexes of children with N-terminal brain natriuretic peptide precursor (NT-proBNP), red blood celldistribution width (RDW), high-sensitivity C-reactive protein (hsCRP), albumin (ALB), sodium (Na + ), and potassium(K+), followed by logistic regression for multivariate analysis. Results These 133 children with heart failure were divid-ed into death group (21 cases) and improved group (112 cases) according to the prognosis. According to the modifiedRoss score, they were divided into mild heart failure group (3 to 6 points) with 68 cases, moderate heart failure group (7to 9 points) with 39 cases, and severe heart failure group (10 to 12 points) with 26 cases. Among them, the death rate ofmild heart failure was 2.9% (2/68 cases), moderate heart failure group was 15.3% (6/39 cases), and severe heart failuregroup was 50.0% (13/26 cases). The single factor analysis showed that RDW, hsCRP and ALB had an impact on theprognosis of children with heart failure (P<0.05). Logistic regression analysis of multiple factors showed that RDW andALB were the risk factors affecting the prognosis of children with heart failure (P<0.05). Conclusion RDW and ALBare risk factors for the prognosis of children with heart failure.
      【Key words】 Children; Heart failure; Regression analysis; Prognosis·论 著·doi:10.3969/j.issn.1003-6350.2018.21.006基金项目：广西壮族自治区卫生厅自筹经费科研课题(编号：Z2014414)